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1.
Radiat Prot Dosimetry ; 115(1-4): 238-41, 2005.
Artigo em Inglês | MEDLINE | ID: mdl-16381719

RESUMO

This work presents results of computer simulation of two experiments which aim at measuring the threshold activation reaction rates in 12C, 19F, 27Al, 59Co, 63Cu, 65Cu, 64Zn, 93Nb, 115In, 169Tm, 181Ta, 197Au, and thin samples placed inside and outside a 0.8 GeV proton-irradiated 4-cm thick W target and a 92-cm-thick W-Na composite target of 15 cm diameter both. In total, more than 1000 values of activation reaction were determined in both the experiments. The measured reaction rates were compared with the rates simulated by the LAHET code with the use of several nuclear databases for the respective excitation functions, namely, MENDL2 together with MENDL2P for cross sections of protons and neutrons up to 100 MeV, and with the recently developed IEAF-2001 that provides neutron cross sections up to 150 MeV. A comparison of simulation-to-experiment agreement obtained with MENDL2 and IEAF-2001 is presented. The agreement between simulation and experiment has been found general satisfactory for both databases. However, further studies should be done to improve the simulation of production of secondary protons and high-energy neutrons, as well as the high-energy neutron elastic scattering. Our results allow to conclude about the reliability of the transport codes and databases used to simulate the accelerator driven systems (ADS), particularly with Na-cooled W targets. High-energy threshold excitation functions to be used in the activation-based unfolding of neutron spectra inside the ADS can also be inferred from these results.


Assuntos
Bases de Dados Factuais , Proteção Radiológica/métodos , Proteção Radiológica/normas , Radioisótopos/análise , Radioisótopos/normas , Radiometria/métodos , Software , Algoritmos , Transferência de Energia , Doses de Radiação , Valores de Referência , Federação Russa
2.
Radiat Prot Dosimetry ; 116(1-4 Pt 2): 585-91, 2005.
Artigo em Inglês | MEDLINE | ID: mdl-16604705

RESUMO

The independent and cumulative measured yields of residual products in thin lead and bismuth targets irradiated with 0.04-2.6 GeV protons are compared with results by the LAHET, CEM03, LAQGSM03, INCL+ABLA, CASCADE and YIELDX codes, in order to evaluate the predictive power of the codes in this energy region. We found that the predictive power of the tested codes is different but is satisfactory for most of the nuclides in the spallation region, though none of the codes agree well with the data in the whole-mass region of product nuclides and all should be improved further. On the whole, the predictive power of all codes for the data in the fission and fragmentation product regions and, especially, at the borders between spallation and fission and between fission and fragmentation regions is much worse than in the spallation region; therefore, development of better evaporation/fission/fragmentation models is of first priority.


Assuntos
Bismuto/química , Bismuto/efeitos da radiação , Chumbo/química , Chumbo/efeitos da radiação , Modelos Químicos , Fissão Nuclear , Software , Simulação por Computador , Relação Dose-Resposta à Radiação , Isótopos/química , Isótopos/efeitos da radiação , Doses de Radiação , Validação de Programas de Computador
3.
Klin Khir ; (8): 14-5, 1999.
Artigo em Ucraniano | MEDLINE | ID: mdl-10584487

RESUMO

The method of intravascular laser irradiation of the blood was applied in complex treatment of 41 patient with thoracic esophagus cancer and in 31 patient with gastroesophageal cancer. Incorporating of photoimmunotherapy to the complex of treatment of patients had promoted the lowering of the postoperative complications rate, mortality and of the three-year survival indexes.


Assuntos
Adenocarcinoma/terapia , Neoplasias Esofágicas/terapia , Neoplasias Gastrointestinais/terapia , Terapia a Laser/métodos , Adulto , Terapia Combinada , Feminino , Seguimentos , Humanos , Imunoterapia/métodos , Masculino , Pessoa de Meia-Idade , Fototerapia/métodos , Complicações Pós-Operatórias/prevenção & controle , Fatores de Tempo , Resultado do Tratamento
4.
Klin Khir ; (5): 27-9, 1999.
Artigo em Ucraniano | MEDLINE | ID: mdl-10429389

RESUMO

Complex treatment of 41 patients with intrathoracic esophageal cancer using intravascular laser irradiation of the blood was done. The immunorehabilitating method application had promoted the postoperative complications rate lowering, the mortality reduction, the three-year survival rate indexes improvement.


Assuntos
Sangue/efeitos da radiação , Braquiterapia/métodos , Carcinoma de Células Escamosas/radioterapia , Endotélio Vascular/efeitos da radiação , Neoplasias Esofágicas/radioterapia , Terapia a Laser , Adulto , Carcinoma de Células Escamosas/cirurgia , Terapia Combinada , Neoplasias Esofágicas/cirurgia , Humanos , Masculino , Pessoa de Meia-Idade , Veias Cavas/efeitos da radiação
5.
Lik Sprava ; (6): 51-5, 1999 Sep.
Artigo em Russo | MEDLINE | ID: mdl-10626443

RESUMO

The authors have developed and approbated a methodology involving the use of copper sulphate as a radio sensitizer. The methods permit the enhancement of the immediate efficiency of treatment up to the level comparative with the best results of radiosensibilization at the expense of cytostatic agents. The incidence of complete regression of the tumor came up to 43.3%, partial one to 53.3%, stabilization to 3.3%. The advantages of the use of copper sulphate include low toxicity, practical availability, and exceptional cheapness, which facts suggest superiority of the proposed methods to other methodologies.


Assuntos
Carcinoma de Células Escamosas/tratamento farmacológico , Sulfato de Cobre/uso terapêutico , Neoplasias Esofágicas/tratamento farmacológico , Radiossensibilizantes/uso terapêutico , Carcinoma de Células Escamosas/sangue , Carcinoma de Células Escamosas/radioterapia , Carcinoma de Células Escamosas/cirurgia , Terapia Combinada , Sulfato de Cobre/efeitos adversos , Neoplasias Esofágicas/sangue , Neoplasias Esofágicas/radioterapia , Neoplasias Esofágicas/cirurgia , Feminino , Humanos , Metástase Linfática , Masculino , Pessoa de Meia-Idade , Cuidados Pré-Operatórios , Radiossensibilizantes/efeitos adversos , Indução de Remissão
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