1.
Bull Exp Biol Med
; 135 Suppl 7: 96-8, 2003 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-12949665
RESUMO
Affinity-purified antibodies to morphine (mixture of homeopathic dilutions C30+C200) produced an antitussive effect on male and female guinea pigs with cough induced by citric acid and capsaicin.
Assuntos
Anticorpos/farmacologia , Antitussígenos/farmacologia , Pulmão/efeitos dos fármacos , Morfina/imunologia , Animais , Antitussígenos/imunologia , Capsaicina/farmacologia , Ácido Cítrico/farmacologia , Tosse/induzido quimicamente , Tosse/tratamento farmacológico , Feminino , Cobaias , Masculino
2.
Bull Exp Biol Med
; 135 Suppl 7: 146-9, 2003 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-12949683
RESUMO
We studied antitussive activity of antibodies to inflammatory mediators (bradykinin, histamine, and serotonin) in ultralow doses. Experiments were performed on guinea pigs with cough induced by citric acid and capsaicin. Test preparations suppressed cough produced by citric acid. Antibodies to bradykinin in ultralow doses were most potent in relieving capsaicin-induced cough (up to 85%); antibodies to serotonin and, particularly, to histamine produced a smaller effect. Potentiated histamine and serotonin possessed polymodal properties.
