RESUMO
INTRODUCTION: Civilizational nature of the cardiovascular diseases, their prevalence and social impact of complications resulting from late diagnosis force to seek new faster and cheaper diagnostic methods. THE AIM: To present a systematic review of the literature on studies of classical and new cardiovascular diseases' risk markers in saliva. MATERIAL AND METHODS: Used database Pubmed, Cochrane from 1980 to 2013 in search of clinical studies of diagnostic tests for saliva in diseases of the cardiovascular system. RESULTS: Saliva sampling for testing is done in a non-invasive and painless way, transport and storage procedures are simpler and less expensive than blood. The diagnostic tests necessary in the diagnosis and treatment of diseases of the cardiovascular system can be performed in saliva. So far, the most promising diagnostic tests are: hs CRP saliva, cortisol, CK-MB, troponin, myoglobin and other biomarkers of inflammation. CONCLUSIONS: Biomarkers of the cardiovascular diseases may be determined in saliva. The use of saliva in the diagnosis is possible and should be applied both to screening assays, as well as in epidemiological and clinical diagnostics.
