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Sci Rep ; 11(1): 2635, 2021 01 29.
Artigo em Inglês | MEDLINE | ID: mdl-33514816

RESUMO

We have developed a process for fabricating patient specific Magnetic Resonance Imaging (MRI) Radio-frequency (RF) receive coil arrays using additive manufacturing. Our process involves spray deposition of silver nanoparticle inks and dielectric materials onto 3D printed substrates to form high-quality resonant circuits. In this paper, we describe the material selection and characterization, process optimization, and design and testing of a prototype 4-channel neck array for carotid imaging. We show that sprayed polystyrene can form a low loss dielectric layer in a parallel plate capacitor. We also demonstrate that by using sprayed silver nanoparticle ink as conductive traces, our devices are still dominated by sample noise, rather than material losses. These results are critical for maintaining high Signal-to-Noise-Ratio (SNR) in clinical settings. Finally, our prototype patient specific coil array exhibits higher SNR (5 × in the periphery, 1.4 × in the center) than a commercially available array designed to fit the majority of subjects when tested on our custom neck phantom. 3D printed substrates ensure an optimum fit to complex body parts, improve diagnostic image quality, and enable reproducible placement on subjects.


Assuntos
Processamento de Imagem Assistida por Computador , Imageamento por Ressonância Magnética/métodos , Nanopartículas Metálicas/química , Prata/química , Humanos , Nanopartículas Metálicas/uso terapêutico , Imagens de Fantasmas , Impressão Tridimensional , Ondas de Rádio , Razão Sinal-Ruído
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