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J Surg Oncol ; 64(1): 68-72; discussion 72-3, 1997 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-9040804

RESUMO

BACKGROUND: In a majority of patients with extremity soft tissue sarcoma, the lungs are the first site at which recurrent disease is detected. Other common sites of recurrence are the resection site, bone metastasis, and liver metastasis. Although abdomino pelvic sarcomatosis is common as a site of recurrence for visceral and retroperitoneal sarcoma, it has not been previously reported for extremity sarcoma. METHOD: We present three patients in whom extremity soft tissue sarcoma metastasized to the peritoneal surfaces, and in all three patients this was symptomatically the dominant site for recurrence. All of them underwent a palliative surgical cytoreduction and were then treated with intraperitoneal chemotherapy. RESULTS: In two of the three patients, isolated progression of peritoneal sarcomatosis has again occurred: one patient remains disease free at 14 months. CONCLUSIONS: Metastasis to peritoneal surfaces within the abdomen and pelvis must be considered a possible site for systemic dissemination of extremity soft tissue sarcomas. Effective treatments for sarcoma spread to peritoneal surfaces would benefit this small but symptomatic group of patients.


Assuntos
Perna (Membro) , Neoplasias Pulmonares/secundário , Neoplasias Peritoneais/secundário , Sarcoma/secundário , Neoplasias de Tecidos Moles/patologia , Adulto , Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico , Neoplasias Ósseas/secundário , Terapia Combinada , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Sarcoma/cirurgia , Sarcoma/terapia , Neoplasias de Tecidos Moles/cirurgia , Neoplasias de Tecidos Moles/terapia
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