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1.
J Cardiothorac Surg ; 19(1): 328, 2024 Jun 10.
Artigo em Inglês | MEDLINE | ID: mdl-38858712

RESUMO

We report a unique case of a 66-year-old man who was incidentally identified to have a mass in the thymus region by computerized tomography scan. CT revealed a well-defined 1.6 × 1 × 0.9 cm thymus mass with moderate uniform enhancement. Thoracoscopic thymectomy was performed, and the pathological diagnosis was primary glomus tumor of the thymus. There were no atypia or malignant histological features, and no primary tumors in other sites. To our knowledge, this is the first case of primary thymic glomus tumor reported in the literature.


Assuntos
Tumor Glômico , Neoplasias do Timo , Tomografia Computadorizada por Raios X , Humanos , Masculino , Idoso , Tumor Glômico/cirurgia , Tumor Glômico/patologia , Tumor Glômico/diagnóstico , Tumor Glômico/diagnóstico por imagem , Neoplasias do Timo/cirurgia , Neoplasias do Timo/patologia , Neoplasias do Timo/diagnóstico , Neoplasias do Timo/diagnóstico por imagem , Timectomia , Timo/patologia , Toracoscopia
2.
Oncol Lett ; 26(4): 461, 2023 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-37745981

RESUMO

Primary synovial sarcoma of the pleura (PSSP) is a rare disease. The present study reported the case of a patient (male; age, 18 years) with two tumors (7.8×2.8 cm and 6.5×5.8 cm) treated with surgery and chemotherapy. To the best of our knowledge, this is the first reported case of two tumors diagnosed as PSSP, which was confirmed by immunohistochemical staining. After six months of follow-up, the symptoms of dry cough and wheezing disappeared and all of the laboratory results were within normal limits. PSSP requires clinical suspicion combined with strategic diagnostic evaluation to confirm the diagnosis and a comprehensive treatment program based on surgery and assisted by chemotherapy.

3.
J Thorac Oncol ; 18(7): 931-939, 2023 07.
Artigo em Inglês | MEDLINE | ID: mdl-36841542

RESUMO

INTRODUCTION: We aimed to prospectively evaluate our previously proposed selective mediastinal lymph node (LN) dissection strategy for peripheral clinical T1N0 invasive NSCLC. METHODS: This is a multicenter, prospective clinical trial in China. We set six criteria for predicting negative LN stations and finally guiding selective LN dissection. Consolidation tumor ratio less than or equal to 0.5, segment location, lepidic-predominant adenocarcinoma (LPA), negative hilar nodes (stations 10-12), and negative visceral pleural invasion (VPI) were used separately or in combination as predictors of negative LN status in the whole, superior, or inferior mediastinal zone. LPA, hilar node involvement, and VPI were diagnosed intraoperatively. All patients actually underwent systematic mediastinal LN dissection. The primary end point was the accuracy of the strategy in predicting LN involvement. If LN metastasis occurred in certain mediastinal zone that was predicted to be negative, it was considered as an "inaccurate" case. RESULTS: A total of 720 patients were enrolled. The median number of LN dissected was 15 (interquartile range: 11-20). All negative node status in certain mediastinal zone was correctly predicted by the strategy. Compared with final pathologic findings, the accuracy of frozen section to diagnose LPA, VPI, and hilar node metastasis was 94.0%, 98.9%, and 99.6%, respectively. Inaccurate intraoperative diagnosis of LPA, VPI, or hilar node metastasis did not lead to inaccurate prediction of node-negative status. CONCLUSIONS: This is the first prospective trial validating the specific mediastinal LN metastasis pattern in cT1N0 invasive NSCLC, which provides important evidence for clinical applications of selective LN dissection strategy.


Assuntos
Adenocarcinoma de Pulmão , Carcinoma Pulmonar de Células não Pequenas , Neoplasias Pulmonares , Humanos , Neoplasias Pulmonares/cirurgia , Neoplasias Pulmonares/patologia , Estudos Prospectivos , Estadiamento de Neoplasias , Carcinoma Pulmonar de Células não Pequenas/patologia , Excisão de Linfonodo , Linfonodos/cirurgia , Linfonodos/patologia , Adenocarcinoma de Pulmão/patologia , Metástase Linfática/patologia , Estudos Retrospectivos
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