Transcatheter Arterial Embolization for Atraumatic Splenic Rupture in TEE-negative Endocarditis: A Case Report.

Introduction: Spontaneous splenic rupture is an extremely rare complication of infective endocarditis. Case Report: We present a case of a 56-year-old immunocompetent female with porcine bioprosthetic mitral valve replacement, automated implanted cardioverter-defibrillator, and atrial fibrillation on apixaban who was found to have in-hospital atraumatic splenic rupture complicating infective endocarditis with Haemophilus parainfluenza. The rupture was treated successfully by endovascular embolization. Usual treatment with six weeks of antibiotics provided durable cure without further complication, and no surgical intervention was needed for either the valve or spleen. Conclusion: Transcatheter arterial embolization should be considered early in atraumatic splenic rupture. Relevant abdominal and cerebral imaging should be considered in all cases of suspected or confirmed infective endocarditis where unexplained symptoms are present.

Implementation and Evaluation of a Trainee Orientation Manual in an Intensive Care Unit Rotation.

Background: The intensive care unit (ICU) rotation places trainees in a fast-paced, high-intensity environment that requires complex patient care and multidisciplinary coordination. Trainees seek continuous medical knowledge acquisition while tasked with learning ICU-specific workflows, procedures, and policies. The unfamiliarity with rotation logistics and administrative roles and expectations could hinder the ICU rotation learning experience. A lack of standardization and material for trainee orientation to administrative ICU tasks and workflows could affect the trainee's rotation performance and overall learner satisfaction. Objective: We evaluated the implementation of an ICU trainee manual to provide trainees with a source of orientation for rotation logistics and nonclinical ICU tasks. We assessd its impact on content retention, learners' satisfaction with the manual, and overall ICU rotation experience. Methods: We designed an observational, prospective cohort study that included all trainees scheduled to rotate in the ICU during the 2020-2021 academic year. The ICU manual was delivered electronically and was available throughout the academic year. Trainees received a survey before their first ICU rotation (pretest) and 6 months after their first ICU rotation (retest) to assess content retention, trainees' perception of the ICU manual, and overall rotation satisfaction. Results: A total of 95 trainees completed the pretest survey, and 61 completed the retest survey. The target cohort response rate for each survey was 100%. Pretest scores were higher than the matched retest scores (41 of 48 [interquartile range, 37-44] vs. 38 of 48 [34-41]; P < 0.001). The median ICU manual satisfaction score was 32 of 40 (26-36.5). We found positive correlations between ICU manual trainee satisfaction score and the retest score (r[59] = 0.320; P = 0.01) and ICU rotation trainee satisfaction level (r[59] = 0.909; P < 0.001). Conclusion: Implementing an ICU manual to orient trainees to their ICU clinical rotation was well received and showed continued retention of orientation content. Higher ICU rotation trainee satisfaction levels were related to a positive perception of the ICU manual.

Fusariosis in Mexico: A 10-year retrospective series.

Fusarium species represent an opportunistic fungal pathogen. The data in Mexico about Fusarium infections in humans are scarce. Here, we present a retrospective series of patients with a confirmed diagnosis of fusariosis in eight different hospitals in Mexico from January 2010 to December 2019. The diagnosis of proven fusariosis was made according to the European Organization for Research and Treatment of Cancer and the Mycoses Study Group Education and Research Consortium (EORT/MSG) criteria. A total of 49 cases were identified in our series. Most patients had burn injuries (49%), and 37% had hematological malignancies. Most patients had fire injuries (40%), followed by electric injuries (8%), febrile neutropenia (10%), and pancytopenia (6%). Patients had skin and soft tissue involvement in 49%, followed by blood culture isolation and biopsies from different sites of the body (lung, sinuses, bone tissue, and eyes). Febrile neutropenia (10%) and fungemia (8%) were the most common clinical syndromes in immunosuppressed patients. Most patients received monotherapy (67%), where voriconazole was used in 30% of the cases, followed by conventional amphotericin B (16%), and lipidic formulations of amphotericin B in 10% (either liposomal amphotericin B or amphotericin B lipid complex). Combination therapy was used in 20% of the cases, and the most common combination therapy was triazole plus any lipidic formulation of amphotericin B (10%). Mortality related to Fusarium infection occurred in 22% of patients. Fusariosis is a serious threat. Burn injuries and hematologic malignancies represent the most common causes of infection in this small series from Mexico.

This study describes the epidemiological characteristics of patients with fusariosis from a multicenter cohort in Mexico. These findings provide information from this invasive fungal disease that threatens different countries in Latin America.

Clostridioides Difficile in Latin America: An Epidemiological Overview.

Clostridioides difficile infection is one of the most significant causes of nosocomial diarrhea associated with antibiotic use worldwide. In recent years, the incidence of Clostridioides difficile infection in Latin American countries has increased due to the emergence and spread of epidemic Clostridioides difficile strains, such as RT027/NAP1/ST1, RT078/ST11, and RT017/ST37; additionally, endemic multi-drug-resistant strains have recently appeared due to the lack of heterogeneous diagnostic algorithms and guidelines for antibiotic use in each country. The aim of this review is to present the latest information regarding Clostridioides difficile and emphasize the importance of epidemiological surveillance of this pathogen in Latin American countries.

Pneumocephalus With Stroke-Like Symptoms: A Rare Complication of Mastoiditis.

Pneumocephalus is defined as the presence of gas or air in the intracranial space and typically arises as a result of neurotrauma. Clinically, pneumocephalus most often presents asymptomatically but may cause headache, nausea, vomiting, and confusion. Pneumocephalus arising from mastoiditis is an unforeseen complication with only a handful of cases reported. We report a case of an elderly male who presented with stroke-like symptoms in the setting of erosive mastoiditis with pneumocephalus.

Is recursive "mindreading" really an exception to limitations on recursive thinking?

The ability to mindread recursively-for example, by thinking what person 1 thinks person 2 thinks person 3 thinks-is a prime example of recursive thinking in which one process, representation, or idea becomes embedded within a similar one. It has also been suggested that mindreading is an exceptional example, with five recursive steps commonly observed for mindreading, in comparison with just one or two in other domains. However, conceptual analysis of existing recursive mindreading tasks suggests that conclusions about exceptional mindreading are insecure. Revised tasks were devised to provide a more rigorous test of recursive mindreading capacity. Study 1 (N = 76) found significantly worse performance at level-5 recursive mindreading on the revised tasks (17% correct) compared with the original tasks (80% correct), and no effect of moderate financial bonuses for good performance. Study 2 (N = 74) replicated poor performance at level-5 recursive mindreading on the revised tasks (15% correct) in the absence of bonuses, but found better performance (45% correct) when participants were offered large bonuses for accuracy, encouraged to take as much time as needed, and assisted with a strategy for recursive reasoning. These findings suggest that, like recursive thinking in other domains, recursive mindreading is effortful and limited. We discuss how the proposed role for high levels of recursive mindreading in communication, culture, and literature might be reconciled with these limitations. (PsycInfo Database Record (c) 2023 APA, all rights reserved).

In vivo delivery of CRISPR-Cas9 genome editing components for therapeutic applications.

Since its mechanism discovery in 2012 and the first application for mammalian genome editing in 2013, CRISPR-Cas9 has revolutionized the genome engineering field and created countless opportunities in both basic science and translational medicine. The first clinical trial of CRISPR therapeutics was initiated in 2016, which employed ex vivo CRISPR-Cas9 edited PD-1 knockout T cells for the treatment of non-small cell lung cancer. So far there have been dozens of clinical trials registered on ClinicalTrials.gov in regard to using the CRISPR-Cas9 genome editing as the main intervention for therapeutic applications; however, most of these studies use ex vivo genome editing approach, and only a few apply the in vivo editing strategy. Compared to ex vivo editing, in vivo genome editing bypasses tedious procedures related to cell isolation, maintenance, selection, and transplantation. It is also applicable to a wide range of diseases and disorders. The main obstacles to the successful translation of in vivo therapeutic genome editing include the lack of safe and efficient delivery system and safety concerns resulting from the off-target effects. In this review, we highlight the therapeutic applications of in vivo genome editing mediated by the CRISPR-Cas9 system. Following a brief introduction of the history, biology, and functionality of CRISPR-Cas9, we showcase a series of exemplary studies in regard to the design and implementation of in vivo genome editing systems that target the brain, inner ear, eye, heart, liver, lung, muscle, skin, immune system, and tumor. Current challenges and opportunities in the field of CRISPR-enabled therapeutic in vivo genome editing are also discussed.

Klebsiella pneumoniae K2 producer of pyogenic liver abscess associated with biliary communication.

INTRODUCTION: Hypervirulent strains of Klebsiella pneumoniae have gained clinical and epidemiological interest because of their capacity to cause severe and life-threatening infections. METHODOLOGY: We report a case involving infection with a hypervirulent K. pneumoniae K2 strain that caused liver abscess in a young woman with type 1 diabetes in Mexico. RESULTS: The infection was found to be associated with biliary tract communication. The virulence factors and capsular serotypes were identified by polymerase chain reaction analysis. After guided drainage and directed antibiotic treatment, the infection resolved and the patient recovered. Colonization of the gastrointestinal tract by hypervirulent K. pneumoniae strains, together with the presence of comorbidity, such as diabetes are important factors that contribute to the development of liver abscess. CONCLUSIONS: The identification of virulent clones is important to understand the pathogenicity and improve control of infections in the patients.

Endemic Thoracic Infections in Latin America and the Caribbean.

Infectious diseases, including parasitic diseases, which are commonly associated with poverty and poor sanitation, continue to cause significant morbidity, disability, and mortality in Latin America and the Caribbean region. This article reviews the epidemiology, pathophysiology, and cardiothoracic imaging manifestation of several communicable diseases endemic to this region.

Dissociation of the Watson-Crick base pairs in vacuum and in aqueous solution: a first-principles molecular dynamics study.

The damage of the DNA structure can affect the correct functioning of the cellular processes. This work investigates the required forces to dissociate the Watson-Crick (WC) base pairs AT into A and T, and GC into G and C. The WC base pairs are immersed in water under realistic conditions of temperature, volume, and density that reproduce the main characteristics of a biological system. The simulations are based on first-principles molecular dynamics combined with steering atomic forces. In addition to the force intensities, the charge transfers between the nucleic acid bases, energy variations, and temperature fluctuations in the cleavage moments are reported. With the purpose of evaluating the effects of the aqueous medium, simulations of the WC base pairs in vacuum are included. The results considering the solvated medium are consistent with the experimental measurements, and show the importance of the aqueous solution to regulate the structural modifications of the nucleic acid bases. The investigation contributes with a novel molecular model in molecular simulations, and to better understand the biological processes where the DNA compounds play an active role in life forms.Communicated by Ramaswamy H. Sarma.

Testicular Germ Cell Tumors: Classification, Pathologic Features, Imaging Findings, and Management.

Testicular germ cell tumors (TGCTs) demonstrate a wide variety of histopathologic, genetic, pathogenetic, and immunocytochemical characteristics and various clinical-biologic profiles and prognoses. Most TGCTs arise from an intratubular precursor cell referred to as germ cell neoplasia in situ (GCNIS), which is an embryonic germ cell with the potential to differentiate into a plethora of embryonic and extraembryonic lineages. Advances in pathologic examination and genetics paved the way for the 2016 World Health Organization (WHO) classification system, which recognizes two pathogenetically distinct groups of TGCTs. Although postpubertal tumors originate from GCNIS, almost all prepubertal tumors belong to the non-GCNIS category. Molecular testing for chromosome 12p amplification helps to distinguish the two tumor categories. Imaging techniques such as US, CT, MRI, and fluorine 18 (18F)-fluorodeoxyglucose PET/CT are pivotal to the diagnosis and staging, evaluation of complications and treatment response, and long-term surveillance of TGCTs. In addition, select MRI findings may help to differentiate a seminoma from a nonseminomatous mixed TGCT. Accurate diagnosis of TGCTs has therapeutic and prognostic implications. Although seminomas show exquisite response to chemotherapy and radiation therapy, postpubertal teratomas are highly resistant to both. The 2016 WHO classification system introduced changes in the diagnosis and management of TGCTs, including the development of new treatment and follow-up guidelines. Radiologists play an essential role in the optimal treatment of patients with TGCTs. Online supplemental material is available for this article. ©RSNA, 2021.

From genome scissors to molecular scalpel: evolution of CRISPR systems.

From bizarre palindromic repeats to a bacterial defense mechanism, to genome editing tool, and more, Clustered Regularly Interspaced Short Palindromic Repeats or CRISPR has significantly impacted the way we study genome modification in less than a decade. In this review, we would like to highlight some key players over 30 years of research and explain this biotechnological tool's basic mechanisms. We also refer to the evolution of the CRISPR variants and some of the applications derived from them. The understanding and upgrading of this system will be a valuable tool in the years to come to solve some of the challenges in diverse fields from pharmaceuticals to therapeutics, from basic plant genetics to crop improvement, from metabolic engineering to waste management and industrial processing.

Teorias subjetivas da convivência escolar: o que os pais dizem? / Teorías subjetivas de la convivencia escolar: ¿qué dicen los padres / Subjective theories about school coexistence: what do parent say?

El objetivo de este trabajo fue describir e interpretar las TS de la convivencia escolar, de un grupo de padres y madres de una escuela de educación primaria chilena. Se utilizó un muestreo teórico y se aplicaron grupos de discusión y entrevistas episódicas a 16 padres y madres de una escuela de educación primaria. Los datos se analizaron mediante la técnica de la teoría fundamentada, encontrando (a) teorías subjetivas simples, pero que disponen a los padres a educar a sus hijos en convivencia; (b) factores asociados a la CE y propuestas para su mejora, (c) además de un rol parental educativo que se organiza en tres niveles para enseñar a sus hijos a convivir en la escuela. En la discusión se analiza la implicancia de estas teorías subjetivas en la convivencia escolar y el rol parental.

O objetivo deste trabalho foi descrever e interpretar as teorias subjetivas (TS) da convivência escolar (CE), de um grupo de pais e mães de uma escola de educação primária chilena. Uma amostragem teórica foi utilizada e se aplicaram grupos de discussão e entrevistas episódicas em 16 pais e mães de uma escola de educação primária. Os dados foram analisados através da técnica da teoria fundamentada (Grounded Theory), encontrando: (a) teorias subjetivas simples, mas que proporcionam aos pais educar seus filhos na convivência; (b) fatores associados à CE e propostas de melhoria; (c) além de um papel educativo dos pais que se organiza em três níveis para ensinar seus filhos a conviver na escola. Na discussão é analisada a implicação das teorias subjetivas na convivência escolar e no papel parental.

The aim of this work was to describe and to interpret subjective theories about school coexistence in a group of parents from a Chilean primary school. A theoretical sample was used, group discussions and episodic interviews were conducted to 16 parents from a primary school. Data was analyzed through grounded theory, finding (a) simple subjective theories lead parents to raise their children on an environment-based approach; (b) associated factors with school coexistence environment and emerging proposals to improve them; (c) as well as a schooling parental role that it organizes around three levels of climate schooling teaching. In the discussion section, we analyze implications of these subjective theories into schooling environment and parental role.

COVID-19 y comportamiento psicológico: revisión sistemática de los efectos psicológicos de las pandemias del siglo XXI

The aim of this work was to conduct a systematic review on psychological behavior in the context of pandemic scenarios during the twenty-first century. We focused on empirical works and brief case reports of H1N1 flu and COVID-19. Our review included 32 papers published both in English or Spanish. We built a set of tables that allowed us to classify the information in four main categories, namely the psychological impact of the pandemic, whether people follow or not official measures to protect themselves against the pandemic, psychological adherence considerations implied as mediators to respect official strategies, and relevant methodological characteristics of the pandemic research. Results show that there are significant impacts on the psychological behavior of people, social groups and organizations in several dimensions, namely emotion, cognition, behavior, mental health, organization and psychosocial factors. In addition, we found that certain social groups experienced a critical psychosocial impact likely due to the pandemic. Psychosocial factors affecting adherence were also identified, which allow us to better understand how health strategies are followed by the population. Different psychosocial suggestions, which emerged from the papers reviewed, were systematized and should be considered as possible pandemic strategies to be implemented.

The damage of the Watson-Crick base pairs by nickel nanoparticles: A first-principles molecular dynamics study.

The nickel nanoparticles are harmful atmospheric pollutants, and the damage caused by them in humans has become a topic of great relevance. In this study we investigate the interaction of the Ni2 and Ni3 clusters with the AT and GC Watson-Crick base pairs in an aqueous medium. Molecular dynamics in combination with density functional theory are employed. A novel method is implemented to create realistic thermodynamic conditions (NVT) in the simulations. The energies, the charges of the interacting compounds, the temperature changes, and the geometric rearrangements are reported. The results show the formation of stable organometallic compounds of the nickel nanoparticles with the DNA nucleic acid bases. In this respect, the biological processes where the DNA is implicated may be altered by the formation of such super-structures.

Bone scan positivity in non-metastatic, castrate-resistant prostate cancer: external validation study

ABSTRACT Introduction: Tables predicting the probability of a positive bone scan in men with non-metastatic, castrate-resistant prostate cancer have recently been reported. We performed an external validation study of these bone scan positivity tables. Materials and Methods: We performed a retrospective cohort study of patients seen at a tertiary care medical center (1996-2012) to select patients with non-metastatic, castrate-resistant prostate cancer. Abstracted data included demographic, anthropometric, and disease-specific data such as patient race, BMI, PSA kinetics, and primary treatment. Primary outcome was metastasis on bone scan. Multivariable logistic regression was performed using generalized estimating equations to adjust for repeated measures. Risk table performance was assessed using ROC curves. Results: We identified 6.509 patients with prostate cancer who had received hormonal therapy with a post-hormonal therapy PSA ≥2ng/mL, 363 of whom had non-metastatic, castrate-resistant prostate cancer. Of these, 187 patients (356 bone scans) had calculable PSA kinetics and ≥1 bone scan. Median follow-up after castrate-resistant prostate cancer diagnosis was 32 months (IQR: 19-48). There were 227 (64%) negative and 129 (36%) positive bone scans. On multivariable analysis, higher PSA at castrate-resistant prostate cancer (4.67 vs. 4.4ng/mL, OR=0.57, P=0.02), shorter time from castrate-resistant prostate cancer to scan (7.9 vs. 14.6 months, OR=0.97, P=0.006) and higher PSA at scan (OR=2.91, P <0.0001) were significantly predictive of bone scan positivity. The AUC of the previously published risk tables for predicting scan positivity was 0.72. Conclusion: Previously published risk tables predicted bone scan positivity in men with non-metastatic, castrate-resistant prostate cancer with reasonable accuracy.

Frecuencia de posiciones de terceros molares impactados en pacientes atendidos en la IPS CES-Sabaneta - Antioquia / Frequency of impacted third molar positions in patients treated in the IPS CES-Sabaneta-Antioquia / Frequência de posições de terceiros molares impactos em pacientes atendidos no IPS CES-Sabaneta - Antioquia

Resumen Introducción y Objetivo: La impactación de terceros molares es una situación clínica muy común en la población mundial; Pell & Gregory han sugerido una clasificación para la impactación basados en la posición horizontal y vertical. Identificar la frecuencia de posiciones de terceros molares impactados en pacientes atendidos en la clínica CES-Sabaneta entre los años 2006-2016. Materiales y métodos: De acuerdo a la base de datos del servicio de cirugía oral, dos examinadores durante 3 meses revisaron 626 historias clínicas en pacientes entre 17 a 28 años de edad que tuvieran formula dental completa, con radiografía panorámica y que fueron remitidos por motivos ortodónticos, restaurativos o quirúrgicos. Resultados: Un total de 515 terceros molares fueron evaluados, el tercer molar más impactado fue el 28 (25,6%), seguido del 18 (25,4%), el 48 con 24,6% y el 38 con 24,2%. Prevaleció el género femenino con 58,6%, el diente más impactado fue el 28 (87.8%), a nivel vertical la posición C fue la que más se impactó, mientras que en los hombres el diente más impactado es el 18 con un 79.7%, la posición B fue la más impactada y a nivel horizontal la clase II fue la más común en ambos sexos. Conclusión: A nivel vertical la posición B, fue la más frecuente en los terceros molares del género femenino, sin embargo, en el género masculino hubo una variación, en el maxilar predomino la posición C; a nivel horizontal la clase II fue las posiciones más frecuentes en ambos géneros.

Abstract Introduction and objective: The Impaction of third molars is a very common clinical situation in the world population; Pell & Gregory have suggested a classification for impaction based on horizontal and vertical position. To identify the frequency of impacted third molar positions in patients treated at the CES-Sabaneta clinic between the years 2006-2016. Materials and methods: According to the oral surgery service database, two examiners during 3 months reviewed 626 clinical histories in patients between 17 and 28 years of ages who had complete dental formula, with panoramic radiography and who were remitted for reasons orthodontic, restorative or surgical. Results: A total of 515 third molars were evaluated, the third most impacted molar was 28 (25.6%), followed by 18 (25.4%), 48 with 24.6% and 38 with 24.2%. %. The female gender prevailed with 58.6%. The most impacted tooth was 28 (87.8%). At the vertical level, position C was the most impacted, while in men the most impacted tooth is 18 with a 79.7. %, position B was the most impacted and at the horizontal level class II was the most common in both sex. Conclusions: At the vertical level, position B was the most frequent in the third molars of the female gender, however in the male gender there was a variation, in the maxillary the position C predominated; A horizontal level class II was the most frequent positions in both sex.

Sumário Introdução e Objetivo: O impacto dos terceiros molares é uma situação clínica muito comum na população mundial; Pell & Gregory sugeriram uma classificação para o impacto com base na posição horizontal e vertical. Identifique a frequência de comprometimento das posições dos terceiros molares em pacientes tratados na clínica CES-Sabaneta entre 2006-2016. Materiais e métodos: Segundo o banco de dados do serviço de cirurgia oral, dois examinadores, durante 3 meses, revisaram 626 prontuários em pacientes entre 17 e 28 anos de idade que possuíam fórmula dental completa, com radiografia panorâmica e foram encaminhados por motivos ortodôntico, restaurador ou cirúrgico. Resultados: Foram avaliados 515 terceiros molares, o terceiro molar mais impactado foi 28 (25,6%), seguido por 18 (25,4%), 48 com 24,6% e 38 com 24,2 % O sexo feminino prevaleceu com 58,6%, o dente mais impactado foi 28 (87,8%), no nível vertical a posição C foi a mais impactada, enquanto nos homens o dente mais impactado é 18 com 79,7%. %, posição B foi a mais impactada e horizontalmente a classe II foi a mais comum em ambos os sexos. Conclusão: No nível vertical, a posição B foi a mais frequente nos terceiros molares do sexo feminino, no entanto, no sexo masculino houve variação, na posição maxilar C predominou; horizontalmente, a classe II foi a posição mais frequente em ambos os sexos.

Mutual Shaping in Swarm Robotics: User Studies in Fire and Rescue, Storage Organization, and Bridge Inspection.

Many real-world applications have been suggested in the swarm robotics literature. However, there is a general lack of understanding of what needs to be done for robot swarms to be useful and trusted by users in reality. This paper aims to investigate user perception of robot swarms in the workplace, and inform design principles for the deployment of future swarms in real-world applications. Three qualitative studies with a total of 37 participants were done across three sectors: fire and rescue, storage organization, and bridge inspection. Each study examined the users' perceptions using focus groups and interviews. In this paper, we describe our findings regarding: the current processes and tools used in these professions and their main challenges; attitudes toward robot swarms assisting them; and the requirements that would encourage them to use robot swarms. We found that there was a generally positive reaction to robot swarms for information gathering and automation of simple processes. Furthermore, a human in the loop is preferred when it comes to decision making. Recommendations to increase trust and acceptance are related to transparency, accountability, safety, reliability, ease of maintenance, and ease of use. Finally, we found that mutual shaping, a methodology to create a bidirectional relationship between users and technology developers to incorporate societal choices in all stages of research and development, is a valid approach to increase knowledge and acceptance of swarm robotics. This paper contributes to the creation of such a culture of mutual shaping between researchers and users, toward increasing the chances of a successful deployment of robot swarms in the physical realm.

[COVID-19 and psychological behavior: a systematic review of the psychological effects of 21st century pandemics]. / COVID-19 y comportamiento psicológico: revisión sistemática de los efectos psicológicos de las pandemias del siglo XXI.

The aim of this work was to conduct a systematic review on psychological behavior in the context of pandemic scenarios during the twenty-first century. We focused on empirical works and brief case reports of H1N1 flu and COVID-19. Our review included 32 papers published both in English or Spanish. We built a set of tables that allowed us to classify the information in four main categories, namely the psychological impact of the pandemic, whether people follow or not official measures to protect themselves against the pandemic, psychological adherence considerations implied as mediators to respect official strategies, and relevant methodological characteristics of the pandemic research. Results show that there are significant impacts on the psychological behavior of people, social groups and organizations in several dimensions, namely emotion, cognition, behavior, mental health, organization and psychosocial factors. In addition, we found that certain social groups experienced a critical psychosocial impact likely due to the pandemic. Psychosocial factors affecting adherence were also identified, which allow us to better understand how health strategies are followed by the population. Different psychosocial suggestions, which emerged from the papers reviewed, were systematized and should be considered as possible pandemic strategies to be implemented.