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10.
Vopr Onkol ; 23(6): 57-61, 1977.
Artigo em Russo | MEDLINE | ID: mdl-919410

RESUMO

The mixture of radionuclides was employed in the concentrations of 100.0, 400.0 and 0.8, 2.0 mc/rat for strontium-90 and cesium-137 in single and chronic administration correspondingly. Prussian blue, sodium alginate and calcium were employed in amounts of 50 mg, 800 mg and 258 mg per rat a day. The data obtained are correlated with the results of the same experiments without using the protection. In compared doses of the irradiation the protective action of the substances under study was noted only in chronic experiments. In this case, the appearance of malignant neoplasms was nearly twice less, and the survival was 120 days longer. The absorbed doses were decreased by 17 times for cesium-137 in the whole body and nearly by 4 times for strontium-90 in the skeleton.


Assuntos
Alginatos/uso terapêutico , Fosfatos de Cálcio/uso terapêutico , Corantes/uso terapêutico , Ferrocianetos/uso terapêutico , Neoplasias Induzidas por Radiação/patologia , Protetores contra Radiação/uso terapêutico , Animais , Fosfatos de Cálcio/administração & dosagem , Radioisótopos de Césio , Corantes/administração & dosagem , Avaliação de Medicamentos , Exposição Ambiental , Feminino , Compostos Férricos/administração & dosagem , Ferrocianetos/administração & dosagem , Protetores contra Radiação/administração & dosagem , Ratos , Sódio/administração & dosagem , Radioisótopos de Estrôncio
13.
Vopr Onkol ; 22(5): 74-8, 1976.
Artigo em Russo | MEDLINE | ID: mdl-779263

RESUMO

The rate of tumor incidence in different rhythms of rat stomach exposure to cesium-137 and strontium-90 was analysed. The correlative values of the administered nucleids activity were selected by analogy with their content in global natural fall-out. In single exposure to the concentrations of 400 and 100 mc/per rat of cesium-137 and strontium-90 mixture accordingly, osteogenic osteosarcomas developed approximatley 4 times as frequently as in chronic administration of the same radionucleids in concentrations of 2 and 8 mc/per rat, correspondingly.


Assuntos
Radioisótopos de Césio , Neoplasias Induzidas por Radiação , Radioisótopos de Estrôncio , Adenoma/etiologia , Neoplasias das Glândulas Suprarrenais/etiologia , Animais , Feminino , Linfoma Difuso de Grandes Células B/etiologia , Neoplasias Experimentais , Osteossarcoma/etiologia , Neoplasias Parotídeas/etiologia , Ratos
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