Conspiracy mentality and health-related behaviour during the COVID-19 pandemic: a multiwave survey in Italy.

OBJECTIVES: This study aimed to (1) explore the changes in conspiracy mentality across the four waves of the COVID-19 pandemic; (2) assess the relationship between conspirative mentality and psychological/behavioural variables; (3) identify the predictors of conspirative mentality; and (4) explore the effect of conspirative mentality on COVID-19 protective behaviour. STUDY DESIGN: This was a multiwave survey. METHODS: A total of 10,013 Italian individuals, aged 18-70 years, were assessed across the four waves (from January to May 2021) through online survey. We collected information about the sociodemographic characteristics of participants, personal experiences of COVID-19 infection, trust, COVID-19 protective behaviours, COVID-19 risk perception, arousal, auto-efficacy, resilience and well-being. Conspiracy mentality was assessed with the Conspiracy Mentality Questionnaire. The statistical analyses included exploratory factorial analyses, Pearson correlations and multiple linear regressions. RESULTS: The conspiracy mentality score during the COVID-19 pandemic was medium-high (mean 59.0 on a 0-100 scale) and slightly increased from 58.2 to 59.9 across months, in parallel with a slight decrease in trust in health institutions and scientific informational sources. Individuals aged >35 years, poorly educated and particularly scared about their financial situation were at risk of showing higher levels of conspirative mentality. Higher levels of conspirative mentality were risk factors for low levels of COVID-19 protective behaviours. CONCLUSIONS: Clear and effective communication may improve trust in health institutions and informational sources, decrease conspirative theories and increase compliance with protective behaviour.

Cortical and Autonomic Stress Responses in Adults with High Versus Low Levels of Trait Anxiety: A Pilot Study.

Stress responses are mediated by complex patterns of cortical and autonomic activity. Earlier studies showed increased recruitment of the right prefrontal cortex (PFC) and parasympathetic withdrawal during a stress task; however, it remains unclear whether these responses change in relation to different levels of psychopathological symptoms, such as trait anxiety. The present study examines the effect of a mathematical task (with a control condition and a stressful/experimental condition) on the PFC and autonomic activity, using a two-channel near infrared spectroscopy (NIRS) and an ECG monitoring system. After a preliminary screening of 65 subjects, a sample of 12 individuals (6 with the highest and 6 with the lowest scores on an anxiety questionnaire, i.e. the STAI trait) was selected. The two groups were similar regarding demographic variables (age, sex, body mass index) and baseline STAI-state scores. Repeated measures ANOVAs were used to compare changes from baseline in oxyhemoglobin (oxy-Hb), heart rate (HR) and root mean square of successive differences (RMSSD) between the two groups. Individuals affected by high levels of trait anxiety showed a reduced bilateral PFC activity during the entire experimental procedure compared to those with low anxiety. No differences in NIRS channels were found between the two groups. During both conditions, RMSSD was lower among individuals affected by high levels of anxious symptoms. Finally, throughout the procedure, changes in HR were higher in the anxious group. Overall, these findings suggest a reduced PFC activity and a larger parasympathetic withdrawal during a stress task in individuals with high levels of trait anxiety compared to those with low anxiety. These results could represent a starting point for future NIRS and ECG studies on the relationship between mental disorders and acute stress responses.

Age-Related Changes in Physiological Reactivity to a Stress Task: A Near-Infrared Spectroscopy Study.

Aging is associated with changes in biological functions, such as reduced cardiovascular responses to stressful tasks. However, less is known about the influence of age on the reactivity of the prefrontal cortex (PFC) to acute stressors. Therefore, this study aimed to investigate the effects of a computerized-controlled stress task on the PFC and autonomic system activity in a sample of older and younger adults. We recruited a total of 55 healthy, right-handed persons (26 older adults with mean age 69.5, SD 5.8 years; and 29 younger adults with mean age 23.8, SD 3.3 years); groups were balanced for sex. Tasks included a control and an experimental condition: during both tasks individuals had to solve simple mental arithmetic problems. For the experimental condition, all participants were faced with a time limit that induced significant stress. Physiological indexes were collected continuously during the entire procedure using a 2-channel near infrared spectroscopy (NIRS) and an ECG monitoring system. Repeated measures ANOVA were used to assess changes in hemoglobin concentrations, and changes in both heart rate and performance outcomes. NIRS, ECG and performance data showed a significant interaction between the group and condition. Post-hoc analyses evidenced a significant increase in heart rate and Oxy-Hb concentration in the bilateral PFC between the control and experimental condition only in the younger group. Post-hoc analyses of behavioral data showed lower percentages of correct responses and higher response times in the older group. In summary, these results suggested that cardiovascular and cortical reactivity to stress tasks are a function of age. Older individuals seem to be characterized by blunted physiological reactivity, suggestive of impaired adaptive responses to acute stressors. Therefore, future studies should investigate the underlying physiological mechanisms of prefrontal and cardiovascular changes related to aging.

[Transient idiopathic hyperphosphatasemia in a rotavirus infection]. / Iperfosfatasemia idiopatica transitoria in corso di infezione da rotavirus.

The paper reports two cases of transitory hyperphosphatasemia in two siblings of 13 and 29 months without modifications of the liver, kidney or bones. Laboratory data are given for hepatic and renal function and for the calcium/phosphorus metabolism. The paper underlines the observation of rotavirus and the consequent clinical symptoms in the two subjects. The hypothesised etiopathogenesis of transitory idiopathic hyperphosphatasemia is referred to a viral mechanism, and to rotavirus in particular.