Skin-effect-mediated magnetoionic control of charge transport in thick layers.

In the rapidly developing area of magnetoionics (MI), which combines electrochemistry and magnetism, changes in the surface chemistry of magnetic materials in response to gate voltages cause dramatic modifications in the magnetic characteristics, resulting in low power-consuming charge transport tuning. Due to the surficial character, only magnetic thin films have been addressed for the MI effect's role in controlling charge transfer. Here, we show how it can be used to regulate the transit of charges in bulk magnetic materials. This is accomplished by combining high-permeability magnetic materials with a high-frequency passing current, allowing the skin effect and the MI effect to control the magnetic materials' impedance due to the impedance's high sensitivity to magnetic permeability. Our in-situ impedance measurement and magneto-optical characterization show the role of redox reactions at the surface in controlling impedance in magnetic materials. This research paves the way for using the MI effect in high-permeability bulk magnetic materials.

Recovery of uranium from phosphate ore in the Sheikh Habil-Iran mine: part I- multivariable optimization of leaching process using the response surface method.

In this research, the recovery of uranium from the phosphate ore of the Sheikh Habil-Iran mine using flotation/calcination-leaching processes has been investigated. A 75-150 µm phosphate ore particle size, sodium oleate as a collector with a concentration of 2,000 g/ton of rock, pH = 10, and 5 min flotation time were obtained as the optimum parameters of flotation using the reverse method, leading to phosphate ore with a grade of 180 ppm UO2, 36.1% P2O5, 7.22% SiO2, and CaO/P2O5 = 1.23. The optimum calcination parameters were selected as 100 µm phosphate ore particles size at D80, 900°C temperature, and 2 h heating time, which resulted in phosphate ore with a grade of 173 ppm UO2 and 31.9% P2O5. An L/S (liquid to solid ratio) = 5, 3 M sulfuric acid concentration, 80°C temperature, and 5 h leaching time were obtained as the optimum leaching parameters using the response surface methodological approach. The efficiency of uranium recovery from phosphate ore pre-treated by flotation and calcination methods was 84.2% and 75.2%, respectively. The results indicated that flotation has superiority over calcination as a pre-treatment method of phosphate ore in the Sheikh Habil-Iran mine.

Incorporation of Al2O3 and ZrO2 ceramics to AZ31 magnesium alloys composite coating using micro-arc oxidation method.

In this research, a composite coating with Al2O3 and ZrO2 particles have been applied on AZ31 magnesium alloy by micro-arc oxidation (MAO) technique. The alkaline electrolyte included a constant based composition and different composition of the Al2O3 and ZrO2 additives. Microstructure observations reveal that the surface pores of composite coating reduced during addition of ZrO2 and Al2O3 ceramic particles. The hardness of coating increased from about 380 for non-added to 620 MPa for Al2O3+ZrO2 added coating and wear rate reduced about 8 times. Wettability of the coating increased by incorporation of Al2O3 and/or ZrO2 particles while, Al2O3 is more effective than ZrO2. Addition of the ceramic particles enhanced the hydrophilicity properties of surface in wettability test and a contact angle of 43° was obtained for coating including Al2O3+ZrO2. The antibacterial properties of MAO coatings showed that S. aureus bacterium is more sensitive to the zirconia and alumina particle than S. typhimurium bacterium after 24 h of incubation.

Developed Low-Temperature Anionic 2H-MoS2/Au Sensing Layer Coated Optical Fiber Gas Sensor.

Carboxyl-functionalized molybdenum disulfide (COOH-MoS2) nanosheets were prepared through a facile low-temperature hydrothermal method. The phase transformation of metallic-1T to 2H-semiconductor COOH-MoS2 nanosheets was conducted through introducing Au thin film on the unclad optical fiber as a sensing layer in a low temperature. The developed structure successfully refined the loss of the semiconducting properties and poor adhesion of COOH-MoS2 on the unclad polymer optical fiber, which provided limited semiconductor potential as the sensing layers on the optical fiber surfaces. The sensing performance of the as-prepared structure was tested for quantitative detection of three different volatile organic carbons (VOCs) of ethanol, propanol, and methanol gases as well as cross-sensitivity to relative humidity. The operating principle was based on intensity variation of the evanescent wave in the sensing region. The response of the proposed sensing system shows maximum response and better linearity (R2 = 0.999) to methanol at room temperature. Finally, the comparative experimental cross-sensitivity to relative humidity and methanol was also studied to evaluate the potential of sensing range.

Association of interleukine-18 polymorphisms with susceptibility to prostate cancer in Iranian population.

Interleukin-18 (IL-18) is a multifunctional cytokine that augments interferon-γ production, promotion of the Th1 immune response and acts as an important immunomediator in the development of some cancers. The current study aimed to analyze the association of the five most common polymorphisms in the IL-18 gene with prostate cancer in the Iranian population. We examined a possible association of IL-18 -137G>C, -607C>A, -656G>T, +105A>C and +127C>T polymorphisms with prostate cancer occurrence by PCR-RFLP assay. Odds ratio (OR) and 95% confidence interval (CI) were used to assess the strength of the association between IL-18 polymorphisms and prostate cancer. Statistical analysis revealed that individuals carrying the mutant homozygote genotype of IL-18 -607C>A (OR=2.251, 95% CI=1.062-4.768, p=0.034) and -137G>C (OR=2.364, 95% CI=1.121-4.984, p=0.024) polymorphisms had an increased risk of prostate cancer. However, for IL-18 -656G>T, +105A>C and +127C>T polymorphisms, there were no differential distributions of their genotypes between patients with prostate cancer and healthy subjects. Our results indicated that the IL-18 -137G>C and -607C>A polymorphisms were significantly associated with an increased risk of prostate cancer in the Iranian population. Thus, these polymorphisms might be used as a molecular biomarker in the early diagnosis of prostate cancer.

Comparison of tactile sensitivity measured with a new digital esthesiometer (Beam Test) relative to Semmes-Weinstein monofilament analog esthesiometer.

The assessment of tactile sensitivity uses many tests, of which monofilaments are considered the best. The aim of this study was to develop a tactile sensitivity test, similar to the monofilament test, which eliminates the error risk related to manipulations by the observer, and to establish a correspondence scale. We studied 29 healthy subjects (18 women and 11 men) with a mean age of 27.8 years. The Semmes-Weinstein monofilament (SWM) analog esthesiometer and a digital beam esthesiometer (DBE) were used. We evaluated the tactile sensitivity threshold on the fingertip of each subject's dominant index using the SWM and the DBE. The DBE test consisted of applying the index against the tip of the beam. During a cycle of four elevations/depressions, the subject would press a button each time he/she felt pressure. The test was repeated three times. The screen displayed an average force value between 0 and 200 allowing the result to be expressed in grams (g). The minimum perceived force was 0.06656g (0.023, 0.166) on average with the SWM test and 0.51773g (0.4824, 0.8062) with the DBE test. Our results confirm the DBE test suppresses the observer's manipulations and that a SWM correspondence scale can be established. With the DBE test, the normal sensation ranged from 0.4824g to 0.757g and light touch decreased from 0.758g to 0.8062g. The threshold value of pathological tactile sensitivity was 0.8063g. The DBE test could therefore be used for preventive diagnosis of carpal tunnel syndrome in occupational medicine.

Geospatial analysis and assessment of 226Ra, 235U, 232Th, 137Cs, and 40K at Anzali wetland, north of Iran.

Achieving better monitoring and radiation risk assessment is among the main issues in environmental studies. In this regard, natural radioactivity measurements in sediments can provide useful information about the environmental transport mechanism and about the sources of radionuclides. Anzali wetland, as the study area of this research, is located on the southwestern shore of the Caspian Sea with rapidly changing ecosystems. Because of its strategic location, increasing pollution levels, decreasing water table, and increasing sediment discharge from rivers, Anzali wetland has a unique significance in terms of studying its radioactivity from sediment and soil samples. The average 226Ra, 235U, 232Th, 137Cs, and 40K values for 33 sediment and soil samples were 24.66, 3.72, 31.94, 11.66, and 506.38 Bq kg-1, respectively. Variography analyses revealed a spatial structure with minimum/maximum variance equal to 3/8 from 135°/45° azimuth direction. In addition, the fractal geometry indicates values higher than 3.7, 24.5, 30, 25, and 475 Bq kg-1 as anomalous values for 235U, 226Ra, 232Th, 137Cs, and 40K using Kriging estimated data with a search radius of 5000 m, respectively. Compared with the average values published by UNSCEAR (2008) for earth's crust average and compared with the values for the southern areas of Iran (Oman Sea), the estimated average and anomalous data for a pollutant at Anzali wetland do not exceed the reference data. The higher values in the samples of this study could be related to specific environmental problems such as industrial wastewater from about 30 polluted factories transported by 10 major rivers. Agricultural wastes, such as herbicides, pesticides, and fertilizers from rice fields, and being a tourist attraction zone at sea beach are the other most possible pollution sources in the study area.

Antibacterial activity of ß -Tricalcium phosphate containing nanosilver particles on periodontal Gram-negative pathogen.

INTRODUCCTION: This research aimed to investigate the effect of antibacterial suspension containing TCP-ß and nanosilver on these pathogens. MATERIAL AND METHODS: Suspension containing concentrations of 4%, 2%, 1% and 0.1% was prepared with tricalcium phosphate and nanosilver. Two control suspensions for pure nanosilver and pure ß-TCP were also prepared. The antibacterial activity of this suspension was investigated on two groups of bacteria, namely, P. intermedia and Aa in thioglycolate broth environment. Subsequently, the MIC was measured for each bacterium. RESULTS: The suspension containing ß-TCP and nanosilver produced an antibacterial effect on P. intermedia and Aa. The effect of this solution on P. intermedia was greater than that on A. actinomycetemcomitans. Moreover, the MICs (mg/mL) for P. intermedia and A. actinomycetemcomitans were 1% and 0.1%, respectively. CONCLUSION: Based on the results of this study adding nanosilver particles to ß-TCP resulted in the antibacterial property of this substance. Specifically, reduced the growth rate of Aa and P. intermedia. Nanosilver can be used to reduce the risk of infection during or after regenerative surgery.

Biochemical and Clinical Features of Insulinoma in a Patient with Turner Syndrome.

Turner syndrome (TS), i.e., mosaic or nonmosaic states with only one normal X chromosome in females, is characterized by a wide spectrum of somatic, hormonal, and metabolic features. Here we report an unusual case of recurrent hypoglycemia in a 53-year-old woman with TS. Biochemical work-up following a 72h fast revealed detectable, inappropriate for low glucose insulin levels and elevated proinsulin and beta-hydroxybutyrate (BOHB) levels. MR and multiphase CT showed a solid 2.5 cm pancreatic tail mass with absent uptake in the 111In-pentetreotide (Octreoscan) scan. Subsequent hepatic vein blood sampling after intra-arterial calcium stimulation showed sharp increase in insulin and modest increase in proinsulin levels. The patient underwent excision of the mass with resolution of symptoms. Histopathologic examination confirmed the neuroendocrine etiology of the tumor. This is, to our knowledge, the third report of TS and concomitant insulinoma. Impaired counterregulatory response to hypoglycemia in patients with TS may result in symptomatic hypoglycemia with only mild insulin elevation and elevated proinsulin in setting of hypoglycemia may be the only indication of insulinoma in these patients. BOHB levels should not be used for ruling out EHH in patients with TS.

Prevalence and main determinants of early post-traumatic thromboembolism in patients requiring ICU admission.

BACKGROUND: Post-traumatic thromboembolism (PE) is now a common challenging particularly in critically ill patients referred to emergency wards. We aimed to identify main factors associated with PE within 72 h of admission after trauma among patients referred to emergency ward. METHODS: In this retrospective study, the database records of 240 patients, with the primary diagnosis of trauma requiring ICU admission and with a final diagnosis of pulmonary embolism, were reviewed. The patients were categorized as the subjects with early pulmonary embolism (≤3 days) and those with late pulmonary embolism (>3 days). RESULTS: According to our analysis, 48.5% of the patients suffered PE faced this event within 72 h of trauma events. The patients in early PE group were older than those who suffered late PE. The prevalence rate of long bone fractures in lower extremities was significantly higher in those with early PE compared with the other patients. The group with early PE had more severe injury when compared to those with later PE. The severe and very severe injuries were indicated in 49.5 and 15.4% in early PE group, and 14.0 and 6.9% in late PE group, respectively. Using the multivariable logistic regression model, older age, presence of long bone fractures, and more severe injury could predict occurrence of early PE in trauma patients referred to emergency ward. CONCLUSION: Occurring early PE is predicted in majority of traumatic patients requiring ICU admission especially in older ones, patients with long bone fractures and those with more severe injury.

Assessment of 226Ra, 238U, 232Th, 137Cs and 40K activities from the northern coastline of Oman Sea (water and sediments).

Water and sediment samples were collected from northern coast of Oman Sea covering from Goatr to Hormoz canyon seaport. Water and sediment quality assessment for naturally or anthropogenic radionuclides at Oman Sea as a main strategic golf for trade and transit, is an important issue. Correspondence analysis (CA) by R-mode analysis represents that sigma(T)-temperature-conductivity-O2 parameters are well-correlated with 226Ra, 232Th and 40K. Accordingly Q-mode analysis revealed an indicator samples of ST13W for different radionuclides, ST03W for O2, and simultaneously ST34W-ST21W-ST08W-ST04W for sigma(T) parameters. The CA results overlapped with factor and cluster analysis results that explained 85.8% of total variance of water samples. Descriptive analysis of sediments indicates more significant variation than water samples. The 232Th and 226Ra generally showing that ST13D to ST25D sediments that restricted to Pi Bashk coastline are concentrated from 137Cs and 40K. By comparison with reference-values from Iran and other parts of the world, they are acceptable with respect to environmental and radioisotope hazards.

In-vitro Study of Photothermal Anticancer Activity of Carboxylated Multiwalled Carbon Nanotubes.

BACKGROUND AND OBJECTIVE: Multi-walled Carbon Nano Tubes (MWCNTs) as an important element of nanosciences have a remarkable absorption in the region of NIR window (650-900 nm) which can overcome the limitations of deep treatment in photothermal therapy. To disperse MWCNTs in water, it is proposed to attach carboxylated functional group (-COOH) to MWCNTs in order to increase dispersivity in water. MATERIALS AND METHODS: A stable suspension of MWCNTs-COOH with different concentrations (from 2.5 to 500 µg/ml) was prepared. Then, they were compared for their ability to increase temperature in the presence of 810 nm laser irradiation and through a wide range of radiation time (from 20 to 600 s) and three laser powers (1.5, 2 and 2.5 w). The temperature rise was recorded real time every 20 seconds by a precise thermometer. RESULTS: Absorption spectrum of MWCNTs-COOH suspension was remarkably higher than water in a wavelength range of 200 to 1100 nm. For example, using the concentrations of 2.5 and 80 µg/ml of MWCNTs-COOH suspension caused a temperature elevation 2.35 and 9.23 times compared to water, respectively, upon 10 min laser irradiation and 2.5 w. Moreover, this predominance can be observed for 1.5 and 2 w radiation powers, too. Our findings show that the maximum of temperature increase was obtained at 80 µg/ml concentration of MWCNT-COOH suspension for three powers and through all periods of exposure time. Our results show that the minimum required parameters for a 5°C temperature increase (a 5°C temperature increase causes cell death) were achieved through 2.5 w, 28 µg/ml concentration and 20 second irradiation time in which both concentration and radiation times were relatively low. CONCLUSION: Our results showed that MWCNTs-COOH can be considered as a potent photothermal agent in targeted therapies. New strategies must be developed to minimize the concentration, irradiation time and radiation power used in experiments.

GIS based analysis of Intercity Fatal Road Traffic Accidents in Iran.

Road traffic accidents including intercity car traffic accidents (ICTAs) are among the most important causes of morbidity and mortality due to the growing number of vehicles, risky behaviors, and changes in lifestyle of the general population. A sound knowledge of the geographical distribution of car traffic accidents can be considered as an approach towards the accident causation and it can be used as an administrative tool in allocating the sources for traffic accidents prevention. This study was conducted to investigate the geographical distribution and the time trend of fatal intercity car traffic accidents in Iran. To conduct this descriptive study, all Iranian intercity road traffic mortality data were obtained from the Police reports in the Statistical Yearbook of the Governor's Budget and Planning. The obtained data were for 17 complete Iranian calendar years from March 1997 to March 2012. The incidence rate (IR) of fatal ICTAs for each year was calculated as the total number of fatal ICTAs in every 100000 population in specified time intervals. Figures and maps indicating the trends and geographical distribution of fatal ICTAs were prepared while using Microsoft Excel and ArcGis9.2 software. The number of fatal car accidents showed a general increasing trend from 3000 in 1996 to 13500 in 2012. The incidence of fatal intercity car accidents has changed from six in 100000 population in 1996 to 18 in 100000 population in 2012. GIS based data showed that the incidence rate of ICTAs in different provinces of Iran was very divergent. The highest incidence of fatal ICTAs was in Semnan province (IR= 35.2), followed by North Khorasan (IR=22.7), and South Khorasan (IR=22). The least incidence of fatal ICTAs was in Tehran province (IR=2.4) followed by Khozestan (IR=6.5), and Eastern Azarbayejan (IR=6.6). The compensation cost of fatal ICTAs also showed an increasing trend during the studied period. Since an increasing amount of money was being paid yearly for the car accidents, which were in their nature preventable, the key players in road safety including governments, car manufacturers, and road developers were recommended to use GIS based accident data for a more efficient planning and budgeting towards the intercity car accidents reduction.

Comparison of postoperative short-term complications after laparoscopic transabdominal preperitoneal (TAPP) versus Lichtenstein tension free inguinal hernia repair: a randomized trial study.

AIM: The aim of this randomized trial was to compare short-term postoperative complications of laparoscopic transabdominal preperitoneal (TAPP) and Lichtenstein tension free hernia repair. METHODS: A total of 120 patients who went inguinal hernia repair at Shahid Sadoughi university training hospital from April 2011 to August 2013 were randomized into two TAPP (N.=60) and Lichtenstein (N.=60) repair group. Follow-up occurred within 6 weeks. The postoperative assessments included pain score (VAS), hematoma/seroma, urinary retention, wound infection incidence, and duration of hospital stay. RESULTS: Pain was the most common symptoms in both groups. The TAPP group patients significantly had experienced less postoperative pain than the Lichtenstein group in all moments (P<0.05). TAPP group had lower incidence of hematoma (TAPP, 6.6% vs. Lichtenstein 13.3%; P=0.67), seroma (TAPP 10% vs. Lichtenstein 13.3%; P=1.00), and infection (TAPP 0 vs. Lichtenstein 1.6%; P=0.67). However, no differences between the 2 groups were found in terms of postoperative complications. In TAPP group mean of hospital stay significantly was less than Lichtenstein group (TAPP, 8.13±2.19 vs. Lichtenstein, 13.15±1.5 days; P<0.001). CONCLUSION: The laparoscopic TAPP repair is safer and less complicated approach to inguinal hernia repair. The two main short-term advantages of the laparoscopic TAPP repair with the tension free Lichtenstein repair were less postoperative pain and earlier return to the normal life activities. No difference was seen in overall complications.

Ketamina a dosis bajas asociada a morfina mejora el control del dolor en urgencias en el paciente con traumatismo / Low-dose ketamine combined with morphine in the hospital emergency department relieves pain and improves trauma patients’ satisfaction

Objetivo: El control del dolor es fundamental en el paciente con traumatismo valorado en un servicio de urgencias hospitalario (SUH). La ketamina es un antagonista del receptor NMDA que asociada a opiáceos podría mejorar el control del dolor. En este estudio se compara la efectividad de la asociación morfina-ketamina respecto a morfinaplacebo, en el control del dolor del paciente con traumatismo. Método: Estudio multicéntrico, aleatorizado y doble ciego. La asignación se ha realizado a través de aleatorización en bloque. Se han incluido 220 pacientes con dolor secundario a traumatismo en extremidades. Han participado tres SUH. Los pacientes se han aleatorizado en dos grupos: un grupo (MK) recibió la dosis habitual de morfina (0,1 mg/Kg) + ketamina (0,1 mg/Kg); el otro grupo (MP) recibió morfina (0,1 mg/Kg) + placebo. El control del dolor se definió como una puntuación igual o inferior a 3 en la escala visual analógica del dolor. La intensidad del dolor y el bienestar de los pacientes se valoraron a los 120 minutos. El análisis se realizó por intención de tratar. Resultados: El grupo MK presentó un mejor control del dolor a los 10 y a los 30 minutos de la administración del tratamiento (p < 0,05) y una menor necesidad de una segunda dosis de analgesia (21,8% vs 39,4%, p = 0,007). Además, el grupo MK recibió una dosis de morfina total menor [8,3 (3,2) mg, vs 9,5 (3,41) mg, p = 0,008] y presentó un mayor alivio del dolor a los 30 min (p < 0,001). Conclusión: La asociación de morfina con ketamina es efectiva para el control y alivio del dolor en el paciente que consulta en los SUH por traumatismo en las extremidades y dolor asociado importante

Background and objective: Pain control is a critical aspect of trauma care in hospital emergency departments. Ketamine is an antagonist of the N-methyl-D-aspartate receptor and co-administration may enhance the effect of opioids. We aimed to compare the efficacy of a morphine-ketamine combination to a morphine-placebo combination in trauma patients. Methods: Multicenter, randomized, double-blind trial. Block randomization was used to assign 220 patients with severe acute pain in 3 hospital emergency departments. One group received the standard dose of 0.1 mg/kg of morphine combined with 0.1 mg/kg of ketamine. The other group received 0.1 mg/kg of morphine with placebo. Effective analgesia was defined by a numerical pain score of 3 or less on a pain scale. Pain severity and patient satisfaction were assessed until 120 minutes after dosing. The data were analyzed on an intention-to-treat basis. Results: Pain was better controlled in the morphine-ketamine group 10 and 30 minutes after administration of the combination (P < .05) and fewer patients required a second analgesic dose (21.8% vs 39.4% in the placebo group, P = .007). The mean (SD) total morphine consumption was 8.29 (3.2) mg in the ketamine group and 9.54 (3.41 mg) in the placebo group (P = .008); the analgesic effect in the ketamine group was superior at 30 minutes (P < .001). Conclusion: The combination of morphine and ketamine provides effective analgesia for hospital emergency department trauma patients with severe acute pain

Does exposure to GSM 900 MHz mobile phone radiation affect short-term memory of elementary school students?

BACKGROUND: Now-a-days, children are exposed to mobile phone radiation at a very early age. We have previously shown that a large proportion of children in the city of Shiraz, Iran use mobile phones. Furthermore, we have indicated that the visual reaction time (VRT) of university students was significantly affected by a 10 min real/sham exposure to electromagnetic fields emitted by mobile phone. We found that these exposures decreased the reaction time which might lead to a better response to different hazards. We have also revealed that occupational exposures to radar radiations decreased the reaction time in radar workers. The purpose of this study was to investigate whether short-term exposure of elementary school students to radiofrequency (RF) radiation leads to changes in their reaction time and short-term memory. MATERIALS AND METHODS: A total of 60 elementary school children ages ranging from 8 to 10 years studying at a public elementary school in Shiraz, Iran were enrolled in this study. Standardized computer-based tests of VRT and short-term memory (modified for children) were administered. The students were asked to perform some preliminary tests for orientation with the VRT test. After orientation, to reduce the random variation of measurements, each test was repeated ten times in both real and sham exposure phases. The time interval between the two subsequent sham and real exposure phases was 30 min. RESULTS: The mean ± standard deviation reaction times after a 10 min talk period and after a 10 min sham exposure (switched off mobile) period were 249.0 ± 82.3 ms and 252.9 ± 68.2 ms (P = 0.629), respectively. On the other hand, the mean short-term memory scores after the talk and sham exposure periods were 1062.60 ± 305.39, and 1003.84 ± 339.68 (P = 0.030), respectively. CONCLUSION: To the best of our knowledge, this is the first study to show that short-term exposure of elementary school students to RF radiation leads to the better performance of their short-term memory.

[The Onco-hematology clinical research unit at the Geneva University Hospital: example of a fruitful public-private partners]. / L'Unité de recherche clinique en onco-hématologie aux HUG: un exemple réussi de partenariat public-privé.

A better understanding of the molecular deregulation leading to carcinogenesis allows the development of numerous novel targeted therapeutic candidates. Clinical research in oncology is a critical step to evaluate in a thorough manner the safety and efficacy of these innovative compounds. During the last four years the fruitful partnership between the Geneva University Hospitals and the Dr. Henri Dubois-Ferriere Dinu Lipatti Foundation lead to a dedicated clinical research unit for cancer patients with a staff of ten people. Since 2010, more than 300 patients were enrolled in more than 70 distinct clinical trials evaluating novel therapies for both solid tumors and hematologic malignancies. Interestingly, classical cytostatic drugs now represent only a small fraction of the new anti-cancer therapies in the pipeline.

Design, development and demonstration of an improved bird washing machine.

Since oil was first extracted, pollution of the seas and oceans or adjacent coasts has been an obstacle for the oil industry and environmental activists. The major concern is oil discharge into the water which may lead to birds' affliction or death, besides putting marine life in jeopardy. This paper presents the first description of the design and implementation of a new bird washing machine that can be utilized for cleaning of oil-coated birds with the minimum of stress. The machine is equipped with a pneumatic system comprised of 19 moving nozzles which evenly cover the bird's body and is designed to be used in contaminated environments where a vast number of birds are affected. Experimental trials show an improvement in operation efficiency compared to other methods in a reduction in washing time, energy consumption and a decrease in fatality rate of washed birds.

Designing a minimum data set for breast cancer: a starting point for breast cancer registration in iran.

BACKGROUND: Due to the high incidence of deaths from breast cancer, high cost of treatment and limited resources, the need to formulate and implement effective programs in reducing the burden of disease is obvious. Care, control and creation of cancer information system having an infrastructure from collection of minimum data sets (MDS) are the top priorities of research in Iran's Ministry of Health. METHODS: This is an applied descriptive research with comparative approach implemented in 2010. MDS for breast cancer on selected countries were searched and reviewed and proposed model based on the country's need was designed. Research data were implemented in 2 stages; assessment of MDS on selected countries and the validation of the proposed model through several meetings that has been carried out by the Undersecretary for Research and Technology and several oncologists and pathologists. RESULTS: The MDS is composed of 11 parameters in the form of fields in closed structured arrangements with consideration to coding responses. These parameters include: hospital data, demography, referral, physical examination and investigation, diagnostic information, pathology, treatment, palliative care, completion of primary treatment, clinical trials and follow-up. This form is available for use in the cancer registry database. CONCLUSION: MDS provides an opportunity to strengthen communication between performed researches and research results for the improvement of programs, policies and strategies and provides positive effect on equality in the health system. Although the stages of creating the MDS for breast cancer has been successful, but many challenges has been met until its completion.

Quality of working life on residents working in hospitals.

BACKGROUND: Residents play an important role in the delivery of hospital care. They regularly work overnight, in emergency situations and with workload and stress which can affect their performance and quality of working life (QWL). This study explores the QWL and its contributory factors in residents working at hospitals affiliated with Tehran University of Medical Sciences (TUMS), Tehran, Iran. METHODS: Medline was searched to identify questionnaires for measuring QWL in healthcare professionals and these questionnaires were used to design a comprehensive questionnaire for measuring residents QWL. Face and content validity of the questionnaire were examined by 7 experts. The questionnaire then was completed twice with one-week interval by 14 residents to assess the intera-rater reliability. Then 310 questionnaires were distributed among residents working at different specialties in 7 hospitals affiliated to TUMS including a large general hospital, two medium general hospitals and four small single specialty hospitals. Statistical analyses were performed by SPSS. RESULTS: Totally, 263 residents (84%) completed the questionnaire. The quality of working life was very well in 18%, well in 32%, moderate in 31%, low in 14% and very low in 5% of residents. Pediatric residents had the highest and urology and internal medicine residents had the lowest quality of working life. CONCLUSION: The QWL is high in the majority of residents, but the QWL is still not desirable in a significant proportion of them. The questionnaire used in this study is reliable and valid. The residents' QWL still need improvement.