RESUMO
DNA analysis was performed in 190 cases of Duchenne and Becker muscular dystrophies (DMD/BMD), including 150 cases with DMD and 40 cases with BMD, using Southern blotting and PCR multiplex techniques with application of 25 pairs of primers. Deletions in the overall material were found in 109 cases: 81 (54%) in patients with DMD and 28 (70%) in patients with BMD. All the deletions in DMD were out of frame with the exception of two cases, whereas in BMD all the deletions but two were in frame. Junction fragments were detected in 12 cases of DMD. In five cases duplications were found: four in patients with DMD and one in a patient with BMD.
RESUMO
A case of a vascular hamartoma occurring in the plantar aspect of the foot is reported. Surgical excision of the mass was the treatment of choice, and the surgery was performed after appropriate diagnostic measures had been undertaken. A normal postoperative course ensued, and no recurrence has been reported.
