[Family doctor: myth or reality?].

A short historic retrospective aspect of family doctor is given. A difference between the family doctor and the doctor of common practice is retraced. Criteria of experience in family doctors' education in different countries are given. Perspectives of the development healthcare system in connection with family medicine orientation are analyzed in the article.

[The importance of the anamnesis and the clinical and paraclinical examination methods in the diagnosis of internal diseases]. / Znachenie anamneza, klinicheskogo i paraklinicheskogo metodov obsledovaniia v diagnostike vnutrennikh boleznei.

Data are available on the studies into the significance of case history, clinical and paraclinical examinations for a valid diagnosis of internal diseases. Clinical cases are presented where neglect of the disease history and detailed clinical examination brought about misdiagnosis. The role of paraclinical methods in diagnostic investigations is considered. It is emphasized that students should be better trained in patients' interviewing and clinical examination.

[A combination of acute leukemia and congenital ectodermal dysplasia]. / O sochetanii ostrogo leikoza s vrozhdennoi éktodermal'noi displaziei.

The authors describe a rare clinical case of associated acute leukemia and congenital ectodermal dysplasia inherited by the autosomal dominant type. Review a problem of disease prediction in patients suffering from such an association.

[Cortisol metabolism in hypertensive patients during the crisis period]. / Metabolizm kortizola u bol'nykh gipertonicheskoi bolezn'iu v period kriza

The examination was conducted in 67 patients with Stage II essential hypertension, aged 29 to 60 years (13 males and 54 females). Cortisol metabolism was assessed on the basis of a study of daily urine excretions of tetrahydrocortisol, tetrahydrocortisone, cortisol, cortisone, 17-oxy-11-desoxycortisol and of their ratio. It is found that in patients with Stage II essential hypertension, beyond the period of exacerbation, cortisol metabolism and the glucocorticoid function of the adrenal cortex are unchanged. During crises the gluococorticoid function of the adrenal cortex is activated, and some changes develop in cortisol metabolism. The severity of the crisis does not affect cortisol metabolism, but results in a growing total secretory activity of the adrenal cortex.