RESUMO
The aim of our study was to evaluate the prognostic value of serum procalcitonine (PCT) assay in adult respiratory infections. Forty-nine patients admitted with pleurisy, community-acquired pneumonia, tuberculosis, infection were included in this prospective study. PCT was assayed on admission and discharge. Biological and clinical parameters of gravity were also evaluated. Twenty patients had elevated PCT of more than 0.50 ng/ml. In 29 patients, PCT was undetectable. The serum PCT level was normal in the patients with tuberculosis, infection, pneumocytosis. PCT did not correlate with the biological and clinical markers of the disease severity but the evolution of PCT correlated with the evolution of C-reactive-protein (r = 0.58, p < 0.05). PCT seems to be an early marker of the evolution of respiratory infections, but it does not help to establish prognosis. Further studies are necessary to assess the potential value of PCT in more severe respiratory infections requiring assisted ventilation.
Assuntos
Calcitonina/sangue , Glicoproteínas/sangue , Precursores de Proteínas/sangue , Infecções Respiratórias/sangue , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Análise de Variância , Biomarcadores , Peptídeo Relacionado com Gene de Calcitonina , Diagnóstico Diferencial , Feminino , Humanos , Modelos Lineares , Masculino , Pessoa de Meia-Idade , Pleurisia/sangue , Pleurisia/diagnóstico , Pneumonia/sangue , Pneumonia/diagnóstico , Pneumonia por Pneumocystis/sangue , Pneumonia por Pneumocystis/diagnóstico , Prognóstico , Estudos Prospectivos , Infecções Respiratórias/diagnóstico , Tuberculose Pulmonar/sangue , Tuberculose Pulmonar/diagnósticoRESUMO
OBJECTIVE: To evaluate the influence of uterine anomalies on the implantation rates after embryo transfer. STUDY DESIGN: A retrospective, multicentric study. This study compare patients presenting a uterine anomaly (septate uterus, umicornuate, pseudonicornuate, bicornuate uterus) having attempted FIVETE between 1987 and 1992 with the normal population treated by IVF, as well as with FIVNAT results. RESULTS: Thirty-eight patients were part of the studied population and total 119 oocyt retrievals which lead to 103 embryo transfers (corresponding to 1.35% of the realised transfers during the same period in the three centers of the study). The pregnancy rate obtained by these patients is significantly lower than those obtained by the control group (11.7% pregnancies by retrievals vs. 19.1%, and 13.6% pregnancies by transfer vs. 24.9%). The implantation rate by embryo transfer is 5.8% in the population studied vs. 11.7% in the control group (P < 0.01). These results significantly improve when the uterine anomaly can be treated (septate uterus). CONCLUSION: The uterine anomalies are associated with a lowered rate of embryo implantation. This implantation rate improves when the anomaly can be treated (septate uterus).
Assuntos
Fertilização in vitro , Útero/anormalidades , Adulto , Implantação do Embrião , Transferência Embrionária , Feminino , Humanos , Infertilidade Feminina/terapia , Gravidez , Estudos RetrospectivosRESUMO
In our study, the rate of pregnancy by transfer and puncture was not significantly different in unexplained and in tubal infertility, but the mean number of transferred embryos was significantly higher in the first group. To explain these data, we compared the quality of embryos in 32 punctures realized among 29 women with unexplained infertility and in 171 punctures planned among 156 women with tubal infertility. The percentage of embryos with 4 or more blastomeres was significantly lower in the unexplained infertility group than in the pure tubal infertility group.
