RESUMO
Peculiarities of myoelectric activity in the gastric corpus, pylorus, and duodenum during acute damage to the stomach and simulated partial intestinal obstruction were studied on cats. During adaptation, the functional systems of digestion organs are characterized by disruption of the relationships between their elements. Disturbances of adaptive processes were accompanied by strengthening of these relationships, which made the whole system more vulnerable.
Assuntos
Obstrução Duodenal/fisiopatologia , Duodeno/fisiopatologia , Piloro/fisiopatologia , Estômago/fisiopatologia , Animais , Gatos , Duodeno/fisiologia , Estimulação Elétrica , Eletromiografia , Eletrofisiologia , Masculino , Piloro/fisiologia , Estômago/fisiologia , Fatores de TempoRESUMO
Functional activity of components of the gastroduodenal complex (gastric cardia, gastric corpus, pylorus, and duodenal bulb) was studied in 4 series of acute experiments. One of these regions was subjected to electrical stimulation in each series. Our results suggest that the cardia possesses rhythm-forming properties, the corpus plays a system-organizing role, the pylorus plays a trigger role, and the duodenal bulb produce synchronizing effects.
Assuntos
Duodeno/fisiologia , Piloro/fisiologia , Estômago/fisiologia , Animais , Gatos , Estimulação Elétrica , Eletricidade , Eletrodos , Eletrofisiologia , Análise MultivariadaRESUMO
Myoelectric activity in various portions of the stomach and duodenum in normal and after vagotomy and intravenous injection of serotonin adipinate was studied in acute experiments on cats. Vagotomy disturbed coordination of myoelectric activity in the stomach and duodenum. Intravenous injection of serotonin adipinate restored coordination and increased myoelectric activity in the stomach, particularly, in the pylorus. Under these conditions the pacemaker of myoelectric activity in the gastric corpus and autonomic regulation of the duodenum were preserved. Intravenous injection of serotonin adipinate most significantly changed myoelectric activity in the pylorus. Myoelectric activity in the cardia increased after vagotomy against the background of serotonin adipinate. Our findings suggest that serotoninergic structures maintain functional heterogeneity of digestive organs and coordinate their interrelationships.
