[Determination of beta-hexosaminidase and gamma-glutamyltranspeptidase activities in urine of pregnant women to monitor alcohol consumption]. / Oznaczanie aktywnosci beta-heksozoaminidazy oraz gamma-glutamylotranspeptydazy w moczu jako markerów spozycia alkoholu przez kobiety ciezarne - doniesienie wstepne.

BACKGROUND: Drinking of alcohol by pregnant women provokes many fetal development disorders, first of all the function of central nervous system and can lead to Fetal Alcohol Syndrome - FAS. AIM: Aims of investigation were to determine beta - hexosaminidase (HEX) and gamma - glutamyltranspeptidase (GGT) activity in the urine to monitoring consumption of alcohol by pregnant women in first trimester and to assess the effect of ethyl alcohol on fetus development. MATERIAL AND METHODS: 22 pregnant women, who did not declare consumption of ethanol containing drinks. The level of creatinine, GGT and HEX in urine was analysed. RESULTS: Preliminary results of our study indicate that determination of GGT and HEX activities could be useful in monitoring of alcohol consumption during pregnancy.