[The case of pleomorphic adenoma in inferior nasal concha]. / Przypadek gruczolaka wielopostaciowego malzowiny nosowej dolnej.

The authors present the case of inferior nasal concha tumor at early growth stage. The tumor which turned out to be pleomorphic adenoma was detected accidentally at 28 years old patient with a nose injury. This localisation of pleomorphic adenoma is extremely rare. The diagnostics, description of surgery and result of a histopathological examination were presented. Reports of a literature of pleomorphic tumors located in atypical places were quoted. Authors emphasize unanimous surgical treatment and necessity of observation after surgery because of tumor recurrence possibility.

[Lack of prognostic significance of carcinoembryonic antigen (CEA) preoperative serum levels in patients with advanced larynx cancer]. / Brak wartosci diagnostycznej przedoperacyjnego oznaczania steienia antygenu rakowo-plodowego (CEA) w surowicy pacjentów z zaawansowanym rakiem krtani.

The purpose of this study was to identify the relationship between preoperative serum levels of carcinoembryonic antigen (CEA) and clinicopathological features in advanced stage of larynx cancer. The mean CEA serum concentrations were below cutoff value, which exclude the CEA as a serum marker in diagnosis of larynx cancer. However, significant correlations were found between CEA levels and tumor size, lymph node metastasis and clinical stage of the disease. The pretreatment CEA level was increased above cut-off value only in 6% of tested patients and thereby is not a prognostic factor in larynx cancer.

[Laser Nd-Yag assisted myringotomy for secretory otitis media in children]. / Myringotomia z zastosowaniem lasera Nd-YAG w leczeniu wysikowego zapalenia ucha srodkowego u dzieci.

The aim of the study was assessment of the qualities of ND-YAG laser assisted myringotomy as a treatment for secretory otitis media. Nd-Yag laser myringotomy was performed on 52 children (104 ears) mean age 6.8 years diagnosed with secretory otitis media and recurrent secretory otitis media (14.4%). Myringotomy was performed under general anesthesia using the laser (CWNd-YAG laser 3100 Sharplan). Adenoidectomy alone or with tonsillotomy was performed at the same time. Laser tympanostomies remained patent for 6-35 days. All tympanostomies healed with no noticeable scarring. In 15 ears pressure equalization tubes were inserted after myringotomy with laser. Septoplasty performed in 5 children. Laser myringotomy appears to be a safe, and easy to performed, alternative technique in the treatment of secretory otitis media.

[Squamous cell carcinoma antigen levels in patients with laryngeal cancer]. / Antygen raka plaskonablonkowego w surowicy krwi pacjentów z rakiem krtani.

Squamous cell carcinoma antigen (SCCAg) is one of the most common markers used in diagnosis of head and neck cancer and larynx cancer. We tested correlations between level of SCC Ag and tumor size, presence of lymph node metastasis, clinical advances of tumour and histopathological diagnosis. Pretreatment level of SCC antigen was evaluated in 34 patients with squamous cell carcinoma of the larynx. Microparticle enzyme immunoassay was used to measure the SCCAg level. Elevated SCCAg serum levels were found in 41% of patients. The magnitude of the marker elevations were correlated with lymph node metastases (N0 versus N2, and N1 versus N2). Our date indicate that in patients with larynx cancer SCCAg does not appear to be a sensitive marker in the primary diagnosis. However, seem to be useful marker for monitoring nodal invasion.

[Granular cell tumour of the larynx--report of two cases]. / Guz abrikosowa krtani--analiza dwóch przypadków.

Granular cell tumour (Abrikosov tumour) of the larynx is an uncommon laryngeal tumour. We report two cases of this rare type of tumor, which were diagnosed and treated at the Department of Otolaryngology of District Hospital in Zamosc in the period 1999-2005. The tumours were detected in two adult men. In the first case (29 years old patient) the tumour was located next to the right arytenoid. The tumour was removed by microlaryngoscopy. In the second case (55 years old patient) the tumour involved half right vocal fold from the posterior commissure. It was removed by laryngofissurae. Both tumours have not recurred after a 5 years follow-up and are still under observation.

[Diagnostic value of tissue polypeptide antigen in serum of larynx cancer patients]. / Wartosc diagnostyczna oznaczania tkankowego antygenu polipeptydowego w surowicy chorych na raka krtani.

UNLABELLED: Tissue polypeptide antigen (TPA) is a serological tumour marker used in the diagnosis, management and follow-up of patients with head and neck cancer. The aim of this study was to evaluate the diagnostic and prognostic significance of pretreatment TPA serum levels in patients with larynx cancer. The predicting ability of this tumour marker with respect to histological type, pathological state and lymph node metastasis was also assessed. MATERIALS AND METHOD: Concentrations of the TPA in the serum from 35 patients were measured by immunoradiometric assay. RESULTS: The results showed the sensitivity value for the group of 35 patients was 29.4%, but in clinical stage IV was 70%. TPA levels correlate with T classification and lymph node metastasis. In T4 tumors it was significantly higher than in T2 (p=0.047). TPA levels were significantly higher in patients with nodal invasion and were generally lower in patients with spinocellular carcinoma (p=0.0048). CONCLUSION: Our date indicate that TPA is of limited usefulness in the primary diagnosis in patients with larynx cancer, but is useful in detecting lymph node metastasis.

[The case of gigantic pleomorphic adenoma of the parotid gland]. / Przypadek olbrzymiego gruczolaka wielopostaciowego slinianki przyusznej.

The authors describe case of big size pleomorphic adenoma of the parotid gland. This tumor lead to cachexia and to elimination of life in society. Attention was paid on the surgical treatment of pleomorphic adenomas by superficial or total parotidectomies. Possibility of the post operative complications avoidance, even in such big cases was emphasized. Recurrence was not observed during 10 months follow up. Use of surgical treatment make that the patient was able to return to her previous job.