[Changes in various indices of the blood-clotting system and lipid levels in patients with depression]. / Izmeneniia nekotorykh pokazatelei sistemy svertyvaniia krovi i urovnia lipidov u bol'nykh depressiei.

Blood coagulation and lipid levels were studied in 60 depressive female patients (schizophrenia--14 patients, manic-depressive psychosis--22 patients, involutional depression--24 patients) and 20 healthy women. The depressive patients showed elevated blood levels of lipids, cholesterol, and fibrinogen, as well as increased antiheparin activity and fibrinolytic depression. The above alterations are regarded as activation of blood coagulation.

[Mechanisms of the development of hypercoagulation in experimental peroxide atherosclerosis]. / Mekhanizmy razvitiia giperkoaguliatsii pri élsperimental'nom perekisnom ateroskleroze.

It is shown that atheroarteriosclerosis develops with attendant hypercoagulation changes in the blood of animals kept on an antioxidant-free diet for 100 days. The changes in blood coagulation are caused by disturbances in the procoagulant properties of the tissue (heart and aorta) cell membranes and those of the red cells. The role of cell membranes in the development of hypercoagulation due to changes in their cell thromboplastic properties is discussed.