[Thanatogenesis of pulmonary tuberculosis based on statistics from tuberculosis hospitals in Moscow]. / Tanatogenez tuberkuleza legkikh po materialam tuberkuleznykh bolnits Moskvy.

Thanatogenesis of pulmonary tuberculosis has been studied on autopsy material gained in tuberculosis hospitals of Moscow from 1972 to 1992. The leading cause of lethal outcomes was progressive fibrous-cavernous tuberculosis (71.6% in 1992). Disseminated tuberculosis mortality rose two-fold (14.2% in 1992). Death rate for infiltrative tuberculosis reaches now 5.56%. Tuberculous patients die of the progressive disease in 54.94%, of respiratory distress and cardiac insufficiency in 32.72%. Progressive tuberculosis proved to combine with nontuberculous diseases in 71.87% of the cases.

[Tissue immunity reactions in experimental aspergillosis]. / Tkanevye reaktsii immuniteta pri éksperimentalnom aspergilleze.

The authors have developed a model of acute and chronic aspergillosis induced by Aspergillus fungi injected intraperitoneally to white mice. Subsequent histological evaluation of the mouse viscera identified 3 phases of tissue immunity reactions: non-specific, characterized by mucosal epithelial proliferation and hypersecretion, lymphoid reaction and development of diffuse alveolitis in the lungs, rapid growth of aspergilla; specific, characterized by pronounced proliferative processes, onset of lymphoid-histiocytic and macrophagal pneumonia, emergence of small thin-wall intraalveolar micetomas, absence of aspergilla growth from homogenates of the internal organs; productive, characterized by formation of granuloma, large aspergillomas in the liver and mesenterium. The course of experimental aspergillosis reflects the process of immunity formation in response to advancing infection.