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1.
Anal Methods ; 14(21): 2051-2062, 2022 06 01.
Artigo em Inglês | MEDLINE | ID: mdl-35546562

RESUMO

Chromatographic fingerprinting provides effective technical means for quality evaluation of traditional Chinese medicine. In this work, a novel multi-wavelength fusion column fingerprint was obtained by intelligent selection of chromatographic peaks from different wavelengths, which displayed the maximum peak area information under the optimal wavelength at the same retention time. Here, the Gardenia jasminoides root was selected as a sample. The multi-wavelength fusion column fingerprint graph of the Gardenia jasminoides root was constructed from five wavelengths (203 nm, 210 nm, 238 nm, 250 nm and 330 nm). The peak capacity, peak resolution, the number of common peaks and similarity were used to evaluate the performance. The 19 batches of Gardenia jasminoides root were classified into three categories with clear distinction between origin categories based on the multi-wavelength fusion column fingerprint combined with chemometrics, including hierarchical cluster analysis and principal component analysis. Nine markers of variation that led to differences between batches were screened by orthogonal partial least squares discriminant analysis. This study demonstrated that the classification model based on the multi-wavelength fusion column fingerprint was better than that on a single-wavelength, and the fusion fingerprint was suitable for the identification and quality control of traditional Chinese medicine with more comprehensive chemical composition information and more accurate prediction ability.


Assuntos
Medicamentos de Ervas Chinesas , Gardenia , Quimiometria , Cromatografia Líquida de Alta Pressão/métodos , Gardenia/química , Controle de Qualidade
2.
Soft Robot ; 7(3): 292-308, 2020 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-31755821

RESUMO

This article describes a novel design of bioinspired soft robotic fingers based upon hybrid jamming principle-integrated layer jamming and particle jamming. The finger combines a fiber-reinforced soft pneumatic actuator with a hybrid jamming substrate. Taking advantage of different characteristics of layer jamming and particle jamming, the substrate is designed with three chambers filled with layers (function as bones) and two chambers filled with particles (function as joints). The layer regions and particle regions are interlocked with each other to guarantee load transfer from the fixed finger end to fingertip. With the proposed design, the finger is endowed with bending shape control, as well as variable stiffness capabilities. Theoretical analysis is conducted to predict the stiffness variation of the proposed finger at different vacuum levels, and experimental tests are performed to evaluate the finger's shape control and stiffness tuning effectiveness. Experimental results show that the proposed finger can achieve 5.52 times stiffness enhancement at primary position. Finally, we fabricate a gripper and perform grasping demonstrations on several objects. Results show that the gripper is able to transfer between low stiffness state for adaptive grasping and high stiffness state for robust holding.


Assuntos
Robótica , Desenho de Equipamento , Dedos , Força da Mão , Robótica/métodos
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