[Actual problems of occupational and environmental hygiene in coal miner towns]. / Aktualnye problemy gigieny truda i okruzhaiushshei sredy v shakhterskikh gorodakh.

The authors present priority directions of occupational diseases prevention nowadays in Kouzbass.

[A concept of prophylaxis for occupational diseases in the Kemerovo region]. / Kontseptsiia profilaktiki professional'nykh zabolevanii v Kemerovskoi oblasti.

The authors represented integral evaluation of sanitary and epidemiologic well-being of people residing in coal miner towns. This evaluation plays an important role in formation of general including children's, occupational and infectious morbidity.

[The mechanism of the development of the epidemic process in Sonne dysentery]. / Mekhanizm razvitiia épidemicheskogo protsessa dizenterii Zonne.

An epidemic outbreak of Sonne dysentery has been studied. The data of epidemiological monitoring before and after the epidemic have been analyzed. The real prognostication value of controlling the biological properties of Shigella sonnei and the increase of their intrapopulation heterogeneity at the period of the activation of the epidemic process of Sonne dysentery has been established.

[The development of the epidemic process and the formation of humoral immunity to the hepatitis A virus in adolescent collectives]. / Razvitie épidemicheskogo protsessa i formirovanie gumoral'nogo immuniteta k virusu gepatita A v podrostkovykh kollektivakh.

Additional observation on the formation of humoral immunity to hepatitis A virus has been carried out in 2,375 adolescents aged 15-17 years and belonging to 12 groups at 3 areas of the USSR. This observation has shown that in the presence of a high level of the immune stratum the spread of infection occurs, as a rule, outside the group under observation. Besides, as revealed in this study, the risk of seroconversion and the loss of specific antibodies are, respectively, directly and inversely related to the level of the immune stratum in the group. The level of the immune stratum in a given age group supposedly reflects the intensity of the development of the epidemic process at a definite area.

[Characteristics of the development of humoral immunity to hepatitis A in children's day care centers]. / Osobennosti formirovaniia gumoral'nogo immuniteta k gepatitu A v kollektivakh detskikh doshkol'nykh uchrezhdenii.

Solid-phase enzyme immunoassay was used to study changes in the frequency and levels of antibody to hepatitis A virus (anti-HAV) in 567 children in 20 isolated groups of 5 day-care centers of the town of Kemerovo. The observation period included the seasonal rise in hepatitis A incidence. An increase in the portion of seropositive children occurred in the groups where manifest or asymptomatic infection with hepatitis A existed. The number of seropositive subjects in the groups where the children were given immunoglobulin by epidemiological indications increased by 0-8%, and in those without immunoglobulin by 11-37.5%. The passive antibody received with immunoglobulin were detected in the originally seronegative children and declined to undetectable levels within 2 months. Subsequently, no clinical cases of hepatitis A or asymptomatic seroconversions were observed in these children. Some cases of reinfection showing an increase in anti-HAV levels but without clinical manifestations of hepatitis A were detected.

[The theory and practice of an epidemic control service for the population]. / Teoriia i praktika protivoépidemicheskogo obsluzhivaniia naseleniia.

The data on the epidemic-control medical care of the population of the Kuznetsk coal fields and on the creation of the specialized system of the epidemiological surveillance of influenza, measles, viral hepatitis, hospital infections are presented. The possibility of using the theory of the self-regulation of the epidemic process in practical work is discussed.