Unusual presentation of immunoglobulin G4-related disease: A case report.

Immunoglobulin G4-related disease (IgG4-RD) is an inflammatory disease characterized by a tumor-like infiltration of IgG4 positive plasma cells and fibrosis in various organs. The exact pathogenesis remains unknown. In this article, we discuss the diagnostic management of IgG4-RD with reference to clinical, serologic, pathological and radiological data on a 17-year-old male patient with lumbar vertebral involvement.

Birth Weight Reference Percentiles by Gestational Age for Turkish Twin Neonates.

AIMS: In clinical practice, birth weight reference percentiles for singletons are used to evaluate twin births. The utilization of singleton reference percentiles for twins is not appropriate as they experience different growth trajectories. However, Turkey still lacks such references. Our aim was to create gestational age-specific birth weight references for female and male Turkish twins. MATERIALS AND METHODS: This is a hospital-based, multi-centered, retrospective study. In total, 2544 live-born twins between 2010 and 2019 were included in the study. Gestational age, birth weight, mode of delivery, gender, birth order, chorionicity, maternal age, pregnancy resulting from assisted reproduction techniques, APGAR (Appearance, Pulse, Grimace, Activity, and Respiration) score at 5 minutes, admission to the neonatal intensive care unit (NICU), length of stay in NICU, and death during the NICU stay were recorded. RESULTS: Smoothed reference curves for birth weight by gestational age and separate tables for female and male twin neonates for the 3rd, 10th, 50th, 90th, and 97th percentiles from 26 to 39 weeks of gestational age were constructed. Overall neonatal and infant mortality rates during NICU stay in our twin cohort were 12/1000 and 16/1000, respectively. CONCLUSION: Twin-specific birth weight nomograms could be helpful as a reference for clinicians to identify high-risk neonates and fetuses who need specialized care. However, further studies with larger series are urgently needed for validation and use of these nomograms in clinical practice.

Progressive bilateral lipoma arborescens of the knee caused by uncontrolled juvenil idiopathic arthritis.

Lipoma arborescens (LA) is a chronic, slowly progressive intra-articular lesion characterized by villous lipomatous proliferation of the synovium. Most cases have been described in elderly patients with degenerative or post-traumatic joint disease, but in several case reports, it has been considered to be related to inflammatory joint diseases. Here, we report a case of 17 years old female firstly presenting with bilateral swelling in both knees of five years duration, followed by the development of wide spread lipoma arborescens associated with the uncontrolled treatment of juvenile idiopathic arthritis.