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Asian Pac J Cancer Prev ; 15(2): 713-6, 2014.
Artigo em Inglês | MEDLINE | ID: mdl-24568484

RESUMO

OBJECTIVE: Connections between chronic inflammation and tumor development and progression are now generally accepted. Recent evidence indicates that hepatitis B is associated with several types of cancer, but whether endometrial carcinoma (EC) is included has not been reported. METHODS: We analyzed HBV serum marker status in 398 patients with endometrial cancer, comparing them to 788 control women undergoing health examination. RESULTS: The total prevalence of HBsAg tested positive in cancer group was significantly higher than the control group (12.8% vs 6.0%, P=0.001), while positive HBsAb was significantly lower (41.2% vs 68.5%, P=0.001). Hepatitis B carriers in endometrial cancer group were also more frequent than in the control group (9.3% vs 5.5%, P=0.013). Interestingly, in the endometrial cancer group, 147 cases were HBV serum marker negative, which was also higher than in the control group (36.9% vs 15.6%, P=0.001). CONCLUSION: There may be a correlation between HBV infection and endometrial carcinoma.


Assuntos
Neoplasias do Endométrio/epidemiologia , Neoplasias do Endométrio/virologia , Vírus da Hepatite B/patogenicidade , Hepatite B/complicações , Adulto , Estudos de Casos e Controles , China/epidemiologia , Neoplasias do Endométrio/sangue , Feminino , Seguimentos , Hepatite B/virologia , Anticorpos Anti-Hepatite B/sangue , Antígenos de Superfície da Hepatite B/sangue , Humanos , Pessoa de Meia-Idade , Estadiamento de Neoplasias , Prevalência , Prognóstico
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