Clinical features, management, and prognosis of Bacillus cereus sepsis in premature neonates.

This study aimed to investigate the clinical characteristics, management and prognosis of Bacillus cereus sepsis in premature neonates. The clinical information of 8 premature neonates with B cereus sepsis who were treated in Shanghai Children Hospital from January 2015 to December 2019 was retrospectively collected from the medical records and analyzed. The neurodevelopment related conditions were collected at follow up visits at corrected age of 6 months and 12 months. Five patients developed meningitis, and cerebral magnetic resonance image showed abnormal in 5 patients. After treatment with meropenem and vancomycin, 1 patient died, and 7 patients survived and were smoothly discharged. At follow up visits, 1 patient was diagnosed with hydrocephalus and showed severely delayed neurodevelopment, 2 patients had mild delayed neurodevelopment, and the neurodevelopment was basically normal in remaining 4 patients. B cereus infection can cause severe complications of central nervous system, and affect neurodevelopmental outcome. Antibiotic treatment with meropenem and vancomycin is proven to be effective. Refreshing the central catheters is helpful for the prevention of B cereus sepsis and cerebral magnetic resonance image may be employed for the prognosis assessment.

Accelerating biodegradation of a monoazo dye Acid Orange 7 by using its endogenous electron donors.

Biodegradation of a monoazo dye - Acid Orange 7 (AO7) was investigated by using an internal circulation baffled biofilm reactor. For accelerating AO7 biodegradation, endogenous electron donors produced from AO7 by UV photolysis were added into the reactor. The result shows that AO7 removal rate can be accelerated by using its endogenous electron donors, such as sulfanilic and aniline. When initial AO7 concentration was 13.6mg/L, electron donors generated by 8h UV photolysis were added into the same system. The biodegradation rate 0.4mg0.05h-1 was enhanced 60% than that without adding electron donor. Furthermore, sulfanilic and aniline were found to be the main endogenous electron carriers, which could accelerate the steps of the azo dye biodegradation.