High Field Electrical Polarization and Magnetoelectric Coupling in Chiral Magnet [Cu(pym)(H2O)4]SiF6·H2O.

The Heisenberg antiferromagnetic chain is a canonical model for understanding many-body gaps that emerge in quantum magnets, and as a result, there has been significant work on this class of materials for much of the past century. Chiral chains, on the other hand, have received markedly less attention. [Cu(pym)(H2O)4]SiF6·H2O (pym = pyrimidine) is an S = 1/2 chiral antiferromagnet with an unconventional spin gap and no long-range ordering at zero field, features that distinguish it from more conventional spin chains that host simple phase diagrams and no magnetoelectric coupling. Here, we report pulsed magnetic field electrical polarization measurements, strong magnetoelectric coupling, and extraordinary magnetic field - temperature phase diagrams for this system. In addition to three low field transitions, we find a series of phase transitions between 40 and 70 T that depend on the magnetic field direction. The observation of electric polarization in a material with a nonpolar crystal structure implies symmetry-breaking magnetic ordering that creates a polar axis - a mechanism that we discuss in terms of significant interactions between the chiral chains as well as Dzyaloshinskii-Moriya effects. Further, we find second-order magnetoelectric coupling, allowing us to deduce the magnetic point group of the highest polarization phase. These findings are in contrast to expectations for an unordered one-dimensional spin chain and reveal a significantly greater complexity of behavior in applied field.

Effects of internal migrants' health on economic resilience in China's Yangtze River Delta urban agglomeration: moderating effects of basic public health services.

Introduction: Internal migrants constitute a significant generality in the socioeconomic development of developing countries. With the frequent occurrence of major public health emergencies, obstacles to labor supply due to health issues among internal migrants not only affect their livelihood stability but also urban economic resilience. Moreover, the design of basic public health service systems tends to favor local residents over internal migrants, further exacerbating the health and employment risks of internal migrants. As a result, urban economic resilience faces significant challenges. Objective: The objective of this study was to deconstruct economic resilience into economic resistance and recovery abilities, investigate the net effect and its heterogeneity of internal migrants' health on economic resilience in China's Yangtze River Delta urban agglomeration (CYRD), and the mediating effect from labor participation rate and labor time supply, as well as the moderating effect of basic public health services. Methods: Based on the China Migrants Dynamic Survey data (CMDS), the study empirically estimated the effects of internal migrants' health on economic resilience in CYRD through microeconometric analysis methods, mediating and moderating effect model. Results: Our findings indicate that internal migrants' health has a positive effect on economic resilience in CYRD. For each unit increase in migrants' health, it will drive up the average economic resistance ability by 0.0186 and the average recovery ability by 0.0039. Secondly, the net effects of migrants' health on economic resilience show significant structural differences, industry and city heterogeneity. The effect of migrants' health on economic resistance ability is significantly higher than that on economic recovery ability; The effect of migrants' health on economic resilience of the secondary industry is higher than that of the tertiary industry; The cities with high economic resistance and recovery abilities have more prominent positive effect from migrants' health. Thirdly, migrants' health not only has a direct effect on the economic resistance and recovery abilities, but also has a mediating effect on which through labor participation rate and labor time supply. Discussion: Enhancing the accessibility and quality of basic public health services is beneficial for enhancing the positive effects of internal migrants' health on economic resilience.

Continuous Spin Excitations in the Three-Dimensional Frustrated Magnet K_{2}Ni_{2}(SO_{4})_{3}.

Continuous spin excitations are widely recognized as one of the hallmarks of novel spin states in quantum magnets, such as quantum spin liquids (QSLs). Here, we report the observation of such kind of excitations in K_{2}Ni_{2}(SO_{4})_{3}, which consists of two sets of intersected spin-1 (Ni^{2+}) trillium lattices. Our inelastic neutron scattering measurement on single crystals clearly shows a dominant excitation continuum, which exhibits a distinct temperature-dependent behavior from that of spin waves, and is rooted in strong quantum spin fluctuations. Further using the self-consistent-Gaussian-approximation method, we determine that the fourth- and fifth-nearest-neighbor exchange interactions are dominant. These two bonds together form a unique three-dimensional network of corner-sharing tetrahedra, which we name as a "hypertrillium" lattice. Our results provide direct evidence for the existence of QSL features in K_{2}Ni_{2}(SO_{4})_{3} and highlight the potential for the hypertrillium lattice to host frustrated quantum magnetism.

Prognostic factors of malignant peritoneal mesothelioma: a retrospective study of 52 female patients.

BACKGROUND: Prognosis in malignant peritoneal mesothelioma (MPM) remains poor, and the associated factors are unclear. Therefore, this study aimed to investigate the prognostic factors of MPM. METHODS: A total of 52 female MPM patients treated in 2012-2017 were retrospectively analyzed. Kaplan-Meier survival curves were generated for survival analysis by the log-rank test. The Cox regression model was used for univariate and multivariate analyses. RESULTS: Univariate analysis showed that median survival time (MST) was longer in the epithelioid type compared with the sarcomatoid type (12 months vs 5 months); cumulative survival rates at 12 months were 45.7% and 0%, respectively (P=0.005). MST was longer in patients with proliferating cell nuclear antigen (Ki67) ≤ 10% compared with those with Ki67 > 10% (15 months vs 11 months). Cumulative survival rates at 12 months were 60.0% and 28.1%, respectively (P=0.036). MSTs in patients administered peritoneal biopsy or adnexectomy + paclitaxel + platinum perfusion, peritoneal biopsy (or adnexectomy) + pemetrexed + platinum perfusion, cytoreductive surgery + paclitaxel + platinum perfusion, and cytoreductive surgery + pemetrexed + platinum perfusion were 6, 11, 12, and 24 months, respectively, with cumulative survival rates at 12 months of 0%, 35.7%, 45.5%, and 73.3%, respectively. Survival time after cytoreductive surgery combined with pemetrexed + platinum was the longest. In multivariate analysis, pathological type, T staging, and therapeutic regimen were independent prognostic factors of MPM (P < 0.05). CONCLUSIONS: Prognosis in MPM is associated with pathological subtype, clinical staging, cytoreductive surgery, and subsequent pemetrexed use. Radical cytoreductive surgery and postoperative use of pemetrexed prolong survival.

Efficacy and safety of metformin in the treatment of gestational diabetes: A protocol for systematic review and meta-analysis.

BACKGROUND: The incidence of gestational diabetes is increasing, which not only cause adverse pregnancy outcomes, but also increases the risk of diabetes for pregnant women and their children. Insulin is the gold standard for the treatment of gestational diabetes, but there are some disadvantages, such as poor patient compliance. Metformin has been used in the treatment of gestational diabetes, but the evaluation of its efficacy and safety is lack of reliable evidence-based medicine evidence. The purpose of this study was to systematically investigate the efficacy and safety of metformin in the treatment of diabetic gestational diabetes. METHODS: Computer searches China National Knowledge Infrastructure, Wanfang, Vipu Information Chinese Journal Service Platform and China Biomedical Database, PubMed, Embase, Web of Science, the Cochrane Library from the establishment of the database to November 2020, randomized controlled clinical trials of metformin in the treatment of gestational diabetes mellitus were conducted in English and Chinese. Two researchers independently carried out data extraction and literature quality evaluation on the quality of the included study, and the included literature was analyzed by Meta using RevMan5.3 software. RESULTS: In this study, the efficacy and safety of metformin in the treatment of diabetic gestational diabetes were investigated by evaluating the outcome indicators of pregnant women and newborn babies respectively. CONCLUSION: This study will provide reliable evidence for the clinical application of metformin in the treatment of diabetic gestational diabetes. ETHICS AND DISSEMINATION: The private information from individuals will not be published. This systematic review also will not involve endangering participant rights. Ethical approval is not required. The results may be published in a peer-reviewed journal or disseminated in relevant conferences. OSF REGISTRATION NUMBER: DOI 10.17605/ OSF.IO / 7RB95.

Design and analysis of a novel virtual gyroscope with multi-gyroscope and accelerometer array.

A new virtual gyroscope with multi-gyroscope and accelerometer array (MGAA) is proposed in this article for improving the performance of angular rate measurement. Outputs of the virtual gyroscope are obtained by merging the signals from gyroscopes and accelerometers through a novel Kalman filter, which intentionally takes the consideration of the MEMS gyroscope error model and kinematics theory of rigid body. A typical configuration of the virtual gyroscope, consisting of four accelerometers and three gyroscopes mounted on designated positions, is initiated to verify the feasibility of the virtual gyroscope with MGAA. Static test and dynamic test are performed subsequently to evaluate its performance. The angular random walk (ARW) and bias instability, two static performance parameters of gyroscope, are reduced from 0.019°/√s and 14.4°/h to 0.0074°/√s and 8.7°/h, respectively. The average root mean square error (RMSE) is reduced from 0.274°/s to 0.133°/s under dynamic test. Compared with the published multi-gyroscope array method, the virtual gyroscope proposed here has a better performance both in static and dynamic tests, with improvement factors of ARW and RMSE about 44.1% and 44.5% higher, respectively.

A miniature shoe-mounted orientation determination system for accurate indoor heading and trajectory tracking.

Tracking the position of pedestrian is urgently demanded when the most commonly used GPS (Global Position System) is unavailable. Benefited from the small size, low-power consumption, and relatively high reliability, micro-electro-mechanical system sensors are well suited for GPS-denied indoor pedestrian heading estimation. In this paper, a real-time miniature orientation determination system (MODS) was developed for indoor heading and trajectory tracking based on a novel dual-linear Kalman filter. The proposed filter precludes the impact of geomagnetic distortions on pitch and roll that the heading is subjected to. A robust calibration approach was designed to improve the accuracy of sensors measurements based on a unified sensor model. Online tests were performed on the MODS with an improved turntable. The results demonstrate that the average RMSE (root-mean-square error) of heading estimation is less than 1°. Indoor heading experiments were carried out with the MODS mounted on the shoe of pedestrian. Besides, we integrated the existing MODS into an indoor pedestrian dead reckoning application as an example of its utility in realistic actions. A human attitude-based walking model was developed to calculate the walking distance. Test results indicate that mean percentage error of indoor trajectory tracking achieves 2% of the total walking distance. This paper provides a feasible alternative for accurate indoor heading and trajectory tracking.

Local Integral Estimates for Quasilinear Equations with Measure Data.

Local integral estimates as well as local nonexistence results for a class of quasilinear equations -Δ p u = σP(u) + ω for p > 1 and Hessian equations F k [-u] = σP(u) + ω were established, where σ is a nonnegative locally integrable function or, more generally, a locally finite measure, ω is a positive Radon measure, and P(u) ~ exp⁡αu (ß) with α > 0 and ß ≥ 1 or P(u) = u (p-1).

A Dual-Linear Kalman Filter for Real-Time Orientation Determination System Using Low-Cost MEMS Sensors.

To provide a long-time reliable orientation, sensor fusion technologies are widely used to integrate available inertial sensors for the low-cost orientation estimation. In this paper, a novel dual-linear Kalman filter was designed for a multi-sensor system integrating MEMS gyros, an accelerometer, and a magnetometer. The proposed filter precludes the impacts of magnetic disturbances on the pitch and roll which the heading is subjected to. The filter can achieve robust orientation estimation for different statistical models of the sensors. The root mean square errors (RMSE) of the estimated attitude angles are reduced by 30.6% under magnetic disturbances. Owing to the reduction of system complexity achieved by smaller matrix operations, the mean total time consumption is reduced by 23.8%. Meanwhile, the separated filter offers greater flexibility for the system configuration, as it is possible to switch on or off the second stage filter to include or exclude the magnetometer compensation for the heading. Online experiments were performed on the homemade miniature orientation determination system (MODS) with the turntable. The average RMSE of estimated orientation are less than 0.4° and 1° during the static and low-dynamic tests, respectively. More realistic tests on two-wheel self-balancing vehicle driving and indoor pedestrian walking were carried out to evaluate the performance of the designed MODS when high accelerations and angular rates were introduced. Test results demonstrate that the MODS is applicable for the orientation estimation under various dynamic conditions. This paper provides a feasible alternative for low-cost orientation determination.

Quaternion-based unscented Kalman filter for accurate indoor heading estimation using wearable multi-sensor system.

Inertial navigation based on micro-electromechanical system (MEMS) inertial measurement units (IMUs) has attracted numerous researchers due to its high reliability and independence. The heading estimation, as one of the most important parts of inertial navigation, has been a research focus in this field. Heading estimation using magnetometers is perturbed by magnetic disturbances, such as indoor concrete structures and electronic equipment. The MEMS gyroscope is also used for heading estimation. However, the accuracy of gyroscope is unreliable with time. In this paper, a wearable multi-sensor system has been designed to obtain the high-accuracy indoor heading estimation, according to a quaternion-based unscented Kalman filter (UKF) algorithm. The proposed multi-sensor system including one three-axis accelerometer, three single-axis gyroscopes, one three-axis magnetometer and one microprocessor minimizes the size and cost. The wearable multi-sensor system was fixed on waist of pedestrian and the quadrotor unmanned aerial vehicle (UAV) for heading estimation experiments in our college building. The results show that the mean heading estimation errors are less 10° and 5° to multi-sensor system fixed on waist of pedestrian and the quadrotor UAV, respectively, compared to the reference path.

[Double-loop cerclage wire No. 10 with the two-part patellar concertration for treatment of patellar comminuted fractures].

OBJECTIVE: To investigate the clinical effects of double-loop cerclage wire No. 10 and the two-part patellar concertration for treatment of comminuted patellar fracture. METHODS: From June 2004 to June 2011, 86 patients with comminuted patellar fracture were treated with double-loop cerclage wire No. 10 and the two-part patellar concertration. They included 48 males and 38 females ranging in age from 19 to 75 (mean 42.5) years. Fifty-two cases were affected in the left and 34 cases in the right, with 3 fracture pieces in 32 cases, 4 fracture pieces in 25 cases and more than 4 fracture pieces in 29 cases. The operation time was 40-70 minutes. The therapeutic effects were evaluated by Bostman patella fractures criteria in all patients. RESULTS: All patients were followed-up for 3 months to 6 years (mean 3.5 years). The overall Bdstman score was (27.65 +/- 2.05). The outcome was excellent in 78 cases and good in 8 cases. CONCLUSION: The double-loop cerclage wire No. 10 and the two-part patellar concertration for comminuted patellar fracture is advantageous due to simplicity, good reduction, stable fixation,early functional exercise, and satisfactory functional recovery.