Tailoring Functional Micromotors for Sensing.

Micromotors are identified as a promising candidate in the field of sensing benefiting from their capacity of autonomous movement. Here, a review on the development of tailoring micromotors for sensing is presented, covering from their propulsion mechanisms and sensing strategies to applications. First, we concisely summarize the propulsion mechanism of micromotors involving fuel-based propulsion and fuel-free propulsion introducing their principles. Then, emphasis is laid to the sensing stratagems of the micromotors including speed-based sensing strategy, fluorescence-based sensing strategy, and other strategies. We listed typical examples of different sensing stratagems. After that, we introduce the applications of micromotors in sensing fields including environmental science, food safety, and biomedical fields. Finally, we discuss the challenges and prospects of the micromotors tailored for sensing. We believe that this comprehensive review can help readers to catch the research frontiers in the field of sensing and thus to burst out new ideas.

Tailoring conductive inverse opal films with anisotropic elliptical porous patterns for nerve cell orientation.

BACKGROUND: The nervous system is critical to the operation of various organs and systems, while novel methods with designable neural induction remain to exploit. RESULTS: Here, we present a conductive inverse opal film with anisotropic elliptical porous patterns for nerve orientation induction. The films are fabricated based on polystyrene (PS) inverse opal scaffolds with periodical elliptical porous structure and poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS) mixed polyacrylamide (PAAm) polymers fillers. It is demonstrated that the anisotropic elliptical surface topography allows the nerve cells to be induced into orientation connected with the stretching direction. Because of the anisotropic features of the film which can be stretched into different directions, nerve cells can be induced to grow in one or two directions, forming a neural network and promoting the connection of nerve cells. It is worth mentioning that the PEDOT:PSS-doped PAAm hydrogels endow the film with conductive properties, which makes the composite films be a suitable candidate for neurites growth and differentiation. CONCLUSIONS: All these features of the conductive and anisotropic inverse opal films imply their great prospects in biomedical applications.