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In 2023, European governments submitted a proposal to comprehensively ban per- and polyfluoroalkyl substances (PFAS), prompting a shift toward PFAS-free alternatives. However, recent research has emphasized the need for an integrated approach to chemical assessment and environmental management rather than abrupt PFAS substitution, as alternatives may pose similar or greater risks. The PFAS Guide was developed to aid corporations in this critical transition. Its goal is to simplify PFAS identification, safe substitution, and gradual elimination. This study applies the Technology Acceptance Model (TAM) to assess how perceived usefulness (PU) and ease of use of the PFAS Guide impact corporate intentions to adopt it. Our analysis, based on responses from 104 European companies, demonstrates a positive link between PU, ease of use, and a company's intent to adopt the PFAS Guide. This underscores the importance of corporations perceiving the PFAS Guide as a valuable and user-friendly resource, given its substantial impact on PFAS phase-out. Descriptive statistics revealed an interesting finding: 51.9% of the participants fell into the "other" group, as outlined in the PFAS Guide. This raises questions regarding the grouping of companies into various sectors. Based on our results, we propose improvements to the PFAS Guide by broadening sector representation to encompass a more diverse range of industries with sector-specific guidance, ensuring content relevance, and accentuating user experience using interactive resources. Future research should focus on the actual adoption and use of the guide to gain deeper insights into adoption rates and long-term PFAS Guide utilization. Furthermore, additional investigations should incorporate subgroup analyses, data triangulation, and a longitudinal approach to enhance our understanding of the factors that support and hinder integrated chemical assessment and environmental management. These research efforts are pivotal in guiding chemical policy and management practices, contributing to a PFAS-free future. Integr Environ Assess Manag 2024;20:1-14. © 2024 The Author(s). Integrated Environmental Assessment and Management published by Wiley Periodicals LLC on behalf of Society of Environmental Toxicology & Chemistry (SETAC).
RESUMO
OBJECTIVE: To correlate patient reports of olfactory dysfunction after surgical intervention for allergic fungal rhinosinusitis (AFRS) with endoscopic findings, psychophysical testing, and quality-of-life scores. DESIGN: A prospective cohort study. SETTING: A tertiary care rhinology clinic at St Paul's Hospital, Vancouver, British Columbia, Canada. PATIENTS: Eighty-one patients with AFRS seen at routine postoperative follow-up. MAIN OUTCOME MEASURES: The Sniffin' Sticks test and a visual analog scale for the perceived olfactory ability of patients with AFRS were administered, along with a 36-Item Short-Form Health Survey. An endoscopic staging score was assigned for each patient. RESULTS: Forty men and 41 women with AFRS underwent olfactory testing; 52 of these individuals completed all parts of the assessment. The mean threshold, discrimination, and identification score was 19 (hyposmic), with a significant correlation between patients' performance on the Sniffin' Sticks test and endoscopic staging, as well as their reported olfactory ability (P < .001 for all 3 tests). The mean score for the 36-Item Short-Form Health Survey was 71, but there was a poor correlation between it and the threshold, discrimination, and identification score; visual analog scale; and endoscopic scores (P > .05 for all 3 tests). CONCLUSION: All patients with AFRS should be evaluated with olfactory testing and treated according to the results.
