Health-related quality of life in men with osteoporosis: a systematic review and meta-analysis.

PURPOSE: The increased social and economic burdens make osteoporosis in men an emerging public health issue. However, the quality of life among men with osteoporosis is still unclear. This systematic review and meta-analysis aimed to evaluate the health-related quality of life (HRQoL) among men with osteoporosis or osteoporotic fracture. METHODS: PubMed, EMBASE, and the Cochrane Library database were systematically searched from inception to May 2021. Studies were included if they used validated questionnaires to measure HRQoL among osteoporotic men. A meta-analysis was performed using a random-effects model or fixed-effects model to calculate the standard mean difference (SMD) or mean difference (MD) with 95% confidential interval (95% CI). RESULTS: 14 studies involving 6338 male participants were chosen for systematic review, of which 10 were included in the meta-analysis. Men with osteoporosis had poorer global HRQoL and multiple dimensions of HRQoL than men without osteoporosis. Hip fracture, vertebral fractures, or wrist fractures dramatically impaired HRQoL of men, and physical function was declined even before hip fracture (SMD = -0.60, 95% CI, -0.82 to -0.39). Femoral and lumbar BMD was positively correlated with HRQoL, and a number of fragility fractures and time since fracture had negative effects on HRQoL. Effective anti-osteoporotic drugs could improve HRQoL of men. CONCLUSION: The health-related life quality of men was significantly impaired by osteoporosis and fracture of the hip, vertebral, or wrist. We should pay more attention to the diagnosis and treatment of male osteoporosis to improve the life quality of men.

[Landscape connectivity of waterbody network in the new reclamation region of Lianyungang based on effective distance model].

Landscape connectivity is an important indicator to measure effectiveness of landscape ecological services. Waterbody connectivity in Lianyun New City, the new reclamation region of Lianyungang, was investigated based on GIS technology and effective distance model. The results showed that the total connectivity of waterbodies was poor in Lanyun New City. Connectivity of patches was related to characteristics of ecological process, ecological services value and spatial arrangement. The higher the ecosystem services value of patches was, the greater its contribution to the overall water landscape connectivity was. Some patches with long strip structure played a key role to improve the landscape connectivity. By classifying the importance of connectivity and functional groups of waterbody patches, planning of waterbodies in Lianyun New City conformed to the theory of non-substitutable pattern developed by Forman. Waterbody patches with corresponding functions should be considered with priority when planning and building a new city. The present study demonstrated that connectivity of patches should be an important factor to be considered in ecological landscape planning. Construction of ecological corridors should not only take the number of ecological landscapes into consideration, but also pay attention to spatial arrangement of landscapes in order to improve the overall landscape connectivity.