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Objective To compare the safety and effectiveness of drug-eluting balloon (DEB) with paclitaxel and drug eluting stent (DES) in treating in-stent restenosis (ISR).Methods The clinical data of a total of 76 patients with ISR,who were admitted to authors' hospital to receive stem implantation during the period from January 2012 to September 2014,were retrospectively analyzed.According to the therapeutic means,the patients were divided into paclitaxel DEB group (n=32) and paclitaxel DES group (n=44).The general clinical information and coronary artery angiography findings were collected.The patients were followed up for one year;the all-cause mortality,cardiac death,myocardial infarction,in-stent thrombosis,target lesion revascularization,target vessel revascularization,and major adverse cardiac events were documented.Results No obvious difference in the general data of patients existed between group DEB and group DES (P＞0.05).The incidences of left anterior descending artery ISR in DEB group and in DES group were 43.75％ and 47.73％ respectively.The ISR target vessel types of the two groups were quite similar (P＞0.05).No statistically significant differences in ISR type,ISR lesion type and characteristics of in-stent restenosis existed between the two groups (P＞0.05).One-year following-up examinations indicated that no statistically significant differences in all-cause mortality,cardiac death,myocardial infarction,in-stent thrombosis,target lesion revascularization,target vessel revascularization,and major adverse cardiac events existed between the two groups (P＞0.05).Further analysis revealed that no significant difference in event-free survival existed between the two groups (P＞0.05).Conclusion For the treatment of ISR,the use of paclitaxel DEB is safe and feasible,its curative effect is not less than DES.
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Objective To explore the related risk factors for bypass graft occlusion in patients within 1 year after coronary artery bypass grafting,in order to provide the basis for the prevention of postoperative bypass graft occlusion.Methods Clinical data of 197 cases treated with coronary artery bypass grafting were collected,and the incidence rate of bypass graft occlusion and its related risk factors were analyzed.Results Graft occlusion occurred in 28 (14.2％) of 197 patients.The incidence rate of bypass graft occlusion were much higher in patients with BMI ≥24 kg/m2,smoking,hypertension,hyperlipemia,diabetes,peripheral vascular diseases and cerebrovascular disease than in patients with BMI ＜24 kg/m2,non-smoking,patients without hypertension,hyperlipemia,diabetes,peripheral vascular diseases or cerebrovascular disease (20.0％ vs.9.8％,22.4％ vs.10.8％,21.2％ vs.3.8％,31.1％ vs.9.2％,23.4％ vs.9.8％,25.5％ vs.10.7％,26.3％ vs.11.3％,x2 =4.106,4.534,11.735,13.658,6.615,6.486,5.656,respectively,P=0.043,0.033,0.001,＜0.001,0.010,0.011,0.017).Smoking,diabetes,hyperlipidemia,peripheral vascular diseases and cerebrovascular disease were the independent risk factors for bypass graft occlusion.Conclusions Many risk factors are related with short-term postoperative bypass graft occlusion in patients with coronary artery bypass grafting.The corresponding control measures should be conducted to decrease the risk of postoperative bypass graft occlusion,aiming directly at the risk factors,especially the independent risk factors.
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Objective To investigate microvascular injury-related factors post-percutaneous coronary intervention (PCI). Methods Seventy-two elderly patients with stable angina , who underwent PCI from February 2009 to February 2014, were enrolled in this study. The index of microvascular resistance (IMR) was assessed and the clinical data were collected. The correlation between general clinical data and the IMR value before and after PCI were analyzed, and regression analysis was conducted on the relevant factors with postoperative microcirculation after PCI. Results After PCI, FFR, CFR, CK-MB, troponin were higher than those before PCI, with significant differences (P < 0.05). Linear regression analysis result showed that glycated hemoglobin, the degree of stenosis after PCI were positively correlated with IMR, but ejection fraction and CFR before PCI were negatively correlated with IMR. Conclusion Clinically, diabetes, severe vascular stenosis, low ejection fraction, low CFR before PCI in patients with unstable angina may likely occur microcirculation after PCI.
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Objective:To observe the therapeutic effect of dual-chamber pacemaker on bradyarrhythmia and analyze its influence on heart function.Methods:A total of 86 patients with bradyarrhythmia undergoing dual-chamber pacemaker implantation were enrolled and followed up for six months.Their clinical symptom scores (evaluated ac-cording Karolinska questionnaire),heart function and improvement of quality of life (QOL)were observed.Re-sults:Compared with before pacemaker implantation,there were significant rise in clinic symptom scores of short breath and acratia [(7.20±5.50)scores vs.(15.00±4.30)scores],dizziness [(3.45±2.20)scores vs.(7.80± 1.40)scores],palpitation [(4.43±1.80)scores vs.(11.00±1.00)scores]and chest pain [(13.25±4.00)scores vs.(20.00±3.00)scores]etc.after implantation of dual-chamber pacemaker,P<0.05 all;there were significant improvements in heart function indexes [cardiac output:(4.12±1.00)L/min vs.(6.90±3.00)L/min,left ven-tricular ejection fraction:(29.80±4.00)% vs.(38.00±3.00)%,cardiac index:(3.20±0.81)L·min-1 ·m-1 vs.(4.31±0.45)L·min-1 ·m-1 ,P<0.01 all],and significant increase in each score and total score of QOL [(12.50±1.00)scores vs.(20.50±2.20)scores]on the third month,and continued until 6 month after implanta-tion (P<0.01 all)in patients with bradyarrhythmia.Conclusion:Dual-chamber pacemaker can significantly im-prove heart function and quality of life in patients with bradyarrhythmia and should be extended in clinic.
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<p><b>OBJECTIVE</b>To study the effect of extubation time of indwelling urinary catheters on postoperative recovery after cesarean section.</p><p><b>METHODS</b>A total of 138 parturients undergoing elective cesarean delivery were randomized into experimental group and control group to have the urinary catheters removed at 6-8 h and 24 h after cesarean section, respectively.</p><p><b>RESULTS</b>Compared with the control group, the experimental group showed significantly decreased incidences of urinary tract infection and urethral irritation (P<0.05), with also a significantly increased rate of autonomous urination and a higher degree of comfort (P<0.05) after removing the catheter.</p><p><b>CONCLUSION</b>A shortened indwelling time of urinary catheters can promote postoperative recovery after cesarean section.</p>
