1.
Angew Chem Int Ed Engl
; 53(1): 225-9, 2014 Jan 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24273002
RESUMO
Direct dehydrative α-alkylation reactions of ketones with alcohols are now realized under simple, practical, and green conditions without using external catalysts. These catalyst-free autocatalyzed alkylation methods can efficiently afford useful alkylated ketone or alcohol products in a one-pot manner and on a large scale by CC bond formation of the in situ generated intermediates with subsequent controllable and selective Meerwein-Pondorf-Verley-Oppenauer-type redox processes.