The pathology biopsy represents the "gold standard" for diagnosis: a case report.

A 70-year-old male with previously unknown immunodeficiency presented with multiple pulmonary nodular shadows observed on chest and abdomen radiography. Fungal infection was detected in brushing specimens, bronchial lavage, and transbronchial lung biopsy samples. Through next-generation sequencing (NGS) analysis, the patient was ultimately diagnosed with disseminated Talaromyces marneffei infection. Treatment with voriconazole at a dosage of 200 mg every 12 hours was initiated. However, after three months of treatment, the patient still had enlarged retroperitoneal lymph nodes, and a lymph node aspiration biopsy was performed to further clarify the diagnosis, which ultimately led to the diagnosis of Talaromyces marneffei infection and B-cell non-Hodgkin's lymphoma. The main significance of this study is to emphasize the importance for clinicians to obtain comprehensive specimens from patients presenting with multiple masses in order to ensure accurate clinical diagnosis.

Analysis of pathological characteristics and nursing intervention of patients with gastric polyps based on image stitching algorithm and endoscopy.

OBJECTIVES: The paper uses image stitching algorithm to understand the clinical and pathological characteristics of gastric polyps under gastroscope, and provides objective basis for the clinical diagnosis and treatment of gastric polyps and nursing intervention. METHODS: The endoscopic, pathological data and surgical conditions of 111 patients with gastric polyps detected in the hospital from January 2017 to August 2019 were retrospectively analyzed. RESULTS: The elderly patients (≥60 years old) in this group were those with high incidence of gastric polyps (56.8%); 80 patients with single polyps (72.1%), 31 patients with multiple polyps (27.9%); polyps were mainly located in the stomach (53.2%); polyps diameter ≤0.5cm are more common (69.4%); polyps are mainly hyperplastic polyps (40.5%) and inflammatory polyps in 37 cases (33.3%). Polyps were removed by biopsy forceps in 30 cases, endoscopic submucosal injection of 0.9% NaCl solution combined with high-frequency electrosurgical removal of 54 cases, endoscopic mucosal resection (EMR) in 6 cases, and endoscopic submucosal dissection (ESD) in treatment of the 4 cases, the remaining 17 cases were treated with surgery, and 12 patients were followed up, 2 of whom relapsed. CONCLUSION: Gastric polyps are small in diameter and mostly single; polyps are mainly located in the stomach body, mainly hyperplastic polyps; treatment methods are mostly endoscopic resection, and there is a possibility of recurrence after polypectomy, and follow-up should be strengthened. Full preparation before the operation, close cooperation during the operation, and careful postoperative care are important links to ensure the safety of the operation and reduce complications such as upper gastrointestinal bleeding.

The efficacy of the problem management model based on the core concept of JCI in gastric polyp patients.

OBJECTIVE: To investigate the therapeutic effect of the problem management model based on the core concept of JCI on painless endoscopic mucosal resection (EMR) in gastric polyp patients. METHODS: A total of 128 patients with gastric polyps who underwent painless EMR in the Department of Gastroenterology in our hospital from January 2019 to February 2020 were recruited as the study cohort and randomly divided into a control group and an experimental group, with 64 patients in each group. The patients in the control group underwent routine nursing intervention, and the patients in the experimental group underwent the problem management model based on the core concept of JCI. The recovery of gastrointestinal function, the stress response [the heart rate (HR) and the mean arterial pressure (MAP)], the psychological status (the SAS and SDS scores), the complications, the hospital stay durations, the nursing quality, and the nursing satisfaction levels were compared between the two groups. RESULTS: After the intervention, the experimental group had earlier first exhaust and defecation times and shorter hospital stay durations than the control group (P<0.05). Both groups had increased HR and MAP, but they were lower in the experimental group than they were in the control group (P<0.05). The SAS and SDS scores were decreased in both groups, and were lower in the experimental group than they were in the control group (P<0.05). The experimental group had a lower incidence of complications than the control group, but the difference was not significantly different (P>0.05). The nursing quality and the nursing satisfaction levels in the experimental group were higher than they were in the control group (P<0.05). CONCLUSION: The problem management model based on the core concept of JCI has a good therapeutic effect on painless EMR in gastric polyp patients. The model is able to effectively reduce the stress response, promote the recovery of postoperative gastrointestinal function, decrease the incidence of complications, and improve the nursing quality and the nursing satisfaction levels.