[Mitochondrial DNA polymorphism in Russian population form five oblasts of the European part of Russia].

New data on mitochondrial DNA polymorphism among Russian population from five oblasts, located within the main ethnic area of Russians, specifically, Ryazan' oblast, Ivanovo oblast, Vologda oblast, Orel oblast, and Tambov oblast (N = 177) are presented. RFLP analysis of the mtDNA coding region showed that most of the mtDNA diversity in the populations examined could be described by main European haplogroups H, U, T, J, K, I, V, W, and X. Haplogroup frequency distribution patterns in the populations of interest were analyzed in comparison with the European and Uralic populations. Based on the haplogroup frequencies, the indices of intraethnic population diversity, Wright's F(st) statistics, and the values of squared deviation from the mean, as well as genetic distances between Russians and European and Uralic populations were estimated. Analysis of these indices along with the anthropological data provided identification of a number of regional groups within the populations examined, which could either result from the interaction of ancient Slavs with different non-Slavic tribes, or could be caused by the ethnic heterogeneity of the ancient Slavs themselves.

[Reaction of mouse hematopoietic stem cells on gamma-irradiation and exposure to tritium oxide]. / Reaktsiia gemopoéticheskikh kolonieobrazuiushchikh kletok myshei na gamma-obluchenie i vozdeistvie okisi tritiia.

In experiments on 600 mice, relative biological effectiveness of tritium oxide was compared to that of gamma-radiation (137Cs) with respect to the response of CFUc. It was shown that RBE of tritium oxide was 1 within the dose range from 0.8 to 0.4 Gy.

[Suppression of bone marrow colony-forming capacity by syngeneic T-lymphocytes in AKR strain mice with lymphoblastic leukemia]. / Ugnetenie kolonieobrazutiushchei sposobnosti kostnogo mozga singennymi T-limfostsitami pri limfoblastnom leikoze u myshei linii AKR.

The effect of lymphocytes from the lymph nodes and thymus on bone marrow colony-forming capacity was studied in AKR mice in the preleukemic and leukemic periods in vivo in the syngeneic donor-recipient system. In the pre-leukemic period, the lymphocytes do not change in the syngeneic stem cell colony-forming index, while in spontaneous lymphoblastic leukemia they suppress bone marrow proliferative activity both in normal and leukemic mice and 62-100%.