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1.
Nat Prod Res ; : 1-19, 2024 May 30.
Artigo em Inglês | MEDLINE | ID: mdl-38813679

RESUMO

Due to the numerous health benefits and therapeutic properties, herbs and plant metabolites/extracts are gaining popularity. This is particularly evident in the current era of drug resistance and the adverse effects of chemical drugs. Ocimum basilicum, also known as basil, has been extensively studied for its pharmacological benefits, including antimicrobial, antifungal, antioxidant, anti-inflammatory, antiviral, and wound healing properties. As a result, this plant has the potential to treat a wide range of diseases in both humans and animals. Ocimum basilicum contains various bioactive chemical compounds, such as neryl acetate, 1,8-cineole, p-allylanisole, geraniol, methyl eugenol, methyl chavicol, and trans-α-bergamotene. The latest advancements in technology can be utilised to enhance the beneficial properties of raw Ocimum basilicum extract. This review compiles and presents the profile of phytocomponents and pharmacological properties of Ocimum basilicum. The findings presented here will contribute to further research on this remarkable herb, aiming to develop effective pharmaceutical solutions for various health issues in humans and animals.

2.
Nanomaterials (Basel) ; 14(7)2024 Mar 28.
Artigo em Inglês | MEDLINE | ID: mdl-38607136

RESUMO

In this study, we used multilayer graphene oxide (GO) obtained by anodic oxidation of graphite powder in 83% sulfuric acid. The modification of GO was carried out by its interaction with hexamethylenediamine (HMDA) according to the mechanism of nucleophilic substitution between the amino group of HMDA (HMDA) and the epoxy groups of GO, accompanied by partial reduction of multilayer GO and an increase in the deformation of the carbon layers. The structure and properties of modified HMDA-GO were characterized using research methods such as scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR), X-ray diffraction spectroscopy and Raman spectroscopy. The conducted studies show the effectiveness of using HMDA-OG for modifying epoxy composites. Functionalizing treatment of GO particles helps reduce the free surface energy at the polymer-nanofiller interface and increase adhesion, which leads to the improvement in physical and mechanical characteristics of the composite material. The results demonstrate an increase in the strength and elastic modulus in bending by 48% and 102%, respectively, an increase in the impact strength by 122%, and an increase in the strength and elastic modulus in tension by 82% and 47%, respectively, as compared to the pristine epoxy composite which did not contain GO-HMDA. It has been found that the addition of GO-HMDA into the epoxy composition initiates the polymerization process due to the participation of reactive amino groups in the polymerization reaction, and also provides an increase in the thermal stability of epoxy nanocomposites.

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