RESUMO
There were performed biochemical and cytological studies of blood in healthy workers of chrysotile asbestos plant in order to determine the functional state of the body, depending on the length of service and working conditions. Mentioned differences between the functional state of the organism were determined in the longitudinal study, under construction on schedule time series with the test group at specified intervals (every year for 7 years surveyed, the same group of healthy workers). The differences between the indices allow one to discriminate different levels of the functional state of the organism for the workers employed at processing complex with experience of 4 and 5 years, and for the employees in the mining and transport workshop with the experience of 5 and 6 years. As a result the work experience of 5 years is considered to be an occupational hazard for workers at processing complex, and 6 years of experience - as an occupational hazard for workers of mining and transport workshop.
Assuntos
Asbestos Serpentinas , Amianto , Indústrias Extrativas e de Processamento/normas , Exposição Ocupacional , Medição de Risco/métodos , Local de Trabalho , Adulto , Feminino , Disparidades nos Níveis de Saúde , Humanos , Cazaquistão/epidemiologia , Estudos Longitudinais , Masculino , Exposição Ocupacional/efeitos adversos , Exposição Ocupacional/análise , Exposição Ocupacional/prevenção & controle , Fatores de Risco , Fatores de Tempo , Local de Trabalho/organização & administração , Local de Trabalho/normasRESUMO
The authors present data of cytogenetic study of workers engaged into chrysotile asbestos industry. Evaluation of chromosomal aberrations in peripheral lymphocytes of workers in main workshops of "Kustanaiskie mineral" JSC revealed reliable increase in chromosomal aberrations level. Structural chromosomal abnormalities in main groups were presented by chromosome and chromatide type aberrations with latter prevelent--that can prove chemical mutagenesis. Chromosome type aberrations were presented by paired fragments and centromere rupture, those of chromatide type--by deletions, single fragments and chromatide ruptures. Higher values of induced mutagenesis were revealed in workers of chrysotile asbestos ore concentration workshop, in workers of ore-preparation workshop, and in individuals with over 25 years of work at chrysotile asbestos production.
