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J Paediatr Child Health ; 53(8): 737-741, 2017 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-28169477

RESUMO

Venous malformations are slow-flow congenital vascular malformations that enlarge as the child ages and may be associated with localised intravascular coagulation, a consumptive coagulopathy characterised by elevated D-dimer and decreased fibrinogen levels. The authors review the known correlations between localised intravascular coagulation and venous malformation number, size and planes involved, and call attention to the concept of the progression of localised intravascular coagulopathy as the child ages and their venous malformations enlarge. The authors also discuss the identified therapeutic options for its investigation, management and treatment, including compression garments, anti-coagulation therapy, sclerotherapy, endovascular laser, surgical excision and sirolimus (rapamycin). Evidence for protocol improvements that may be instigated for the optimal physical and medical therapy of venous malformations complicated by localised intravascular coagulopathy is reviewed.


Assuntos
Anticoagulantes/uso terapêutico , Coagulação Intravascular Disseminada/sangue , Coagulação Intravascular Disseminada/tratamento farmacológico , Malformações Vasculares/etiologia , Aspirina/uso terapêutico , Criança , Fibrina/uso terapêutico , Heparina/uso terapêutico , Humanos , Fatores de Risco
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