RESUMO
Evaluations of immune system of 155 patients with rubella and 90 contacts with patients were examined. Detection of viral genetic material in blood, urine, and nasopharyngeal swabs has been performed using RT-PCR method. Clinical diagnosis has been confirmed by RT-PCR in 114 (73.5%) patients. Changes of laboratory tests for rubella without clinical signs of the infection were observed in 20% of contacts. Complex ELISA- and PCR-assisted examination of patients can help to determine the stage of disease and characteristics of immune response. For differential diagnostic of rubella and other infectious diseases with exanthema it is rational to perform complex examination of patients using immunologic and molecular biologic methods.
Assuntos
Anticorpos Antivirais/sangue , Vírus da Rubéola/imunologia , Rubéola (Sarampo Alemão)/imunologia , Adolescente , Adulto , Anticorpos Antivirais/imunologia , Afinidade de Anticorpos , Portador Sadio/diagnóstico , Portador Sadio/imunologia , Criança , Pré-Escolar , Progressão da Doença , Ensaio de Imunoadsorção Enzimática , Feminino , Humanos , Lactente , Masculino , RNA Viral/análise , Reação em Cadeia da Polimerase Via Transcriptase Reversa , Rubéola (Sarampo Alemão)/diagnóstico , Rubéola (Sarampo Alemão)/virologia , Vírus da Rubéola/genética , Vírus da Rubéola/isolamento & purificação , SibériaAssuntos
Hepatite B/complicações , Doença de Hodgkin/complicações , Interferon Tipo I/uso terapêutico , Leucemia/complicações , Linfoma não Hodgkin/complicações , Peptídeos/uso terapêutico , Extratos do Timo/uso terapêutico , Adolescente , Criança , Pré-Escolar , Hepatite B/imunologia , Doença de Hodgkin/imunologia , Humanos , Leucemia/imunologia , Linfoma não Hodgkin/imunologiaRESUMO
High-sensitivity methods were employed to test blood serum for hepatitis B markers in 293 infant cancer patients. HBsAg was identified in 31.7 while anti-HBs--in 16.7% of cases. Hepatitis B markers most frequently occurred in patients suffering from lymphoproliferative diseases (60.1%). HBeAg was detected in 46.5% of patients with HBsAg. The results point to a high incidence of hepatitis B virus in cancer patients.
