RESUMO
The authors discuss a case of thrombocytopenia with bleeding occurred in a young woman with infectious mononucleosis admitted to the Infectious Disease Department of University of Catania. It is reported the pathogenetic hypothesis of virus-induced thrombocytopenia and therapy.
Assuntos
Mononucleose Infecciosa/complicações , Trombocitopenia/etiologia , Doença Aguda , Adulto , Terapia Combinada , Feminino , Humanos , Mononucleose Infecciosa/diagnóstico , Mononucleose Infecciosa/terapia , Contagem de Plaquetas , Trombocitopenia/diagnóstico , Trombocitopenia/terapiaRESUMO
The prevalence of anti-HCV antibodies was determined for a group of 68 patients with various forms of chronic liver disease. All patients that were anti-HCV positive but did not show signs of HBV replication had severe liver disease. We therefore suggest that HCV may be responsible for liver damage in HBsAg positive subjects when there are no evident signs of HBV replication.
Assuntos
Hepatite B/complicações , Hepatite C/complicações , Hepatopatias/complicações , Doença Crônica , Feminino , Anticorpos Anti-Hepatite/sangue , Hepatite B/imunologia , Anticorpos Anti-Hepatite B/sangue , Antígenos de Superfície da Hepatite B/imunologia , Hepatite C/imunologia , Humanos , Masculino , Pessoa de Meia-Idade , Estudos RetrospectivosRESUMO
In a study of 175 intravenous drug addicts from Eastern Sicily, 58.3% were found to be anti-HCV positive. In this population, the presence of anti-HCV was independent of HIV infection, age, duration of drug use and the practice of needle sharing. This may indicate that HCV is more readily transmitted (or spread earlier in this population) among drug addicts than is HIV.