Awareness and knowledge of heterozygous familial hypercholesterolemia among Serbian pediatricians.

Objective: Published reports describing awareness and knowledge of familial hypercholesterolemia (FH) among pediatricians are few and differ considerably across countries. We aimed to assess awareness and knowledge of the FH among pediatricians in Serbia. Methods: A web-based cross-sectional study using a self-designed questionnaire was conducted during the annual congress of the Serbian Association of Preventive Pediatrics in 2020. Results: A total of 141 pediatricians completed the questionnaire (response rate 16.1%). Overall, 91% of participants have knowledge about genetic inheritance of FH, 84.3% were aware of long-term health risks of FH, 77% were familiar with normal cholesterol values in children and 71% knew the FH prevalence in the general population. On the other hand, only 36.8% declared that they were familiar with international guidelines for FH drug treatment and only 26.2% declared to have patients with FH. Conclusion: There is a substantial lack of practical clinical knowledge among Serbian pediatricians on managing children with FH. In addition, an extremely low questionnaire response rate (16.1%) suggests that most pediatricians are not aware of the clinical importance of FH in childhood.

The effects of the aerobic endurance running program on the morphological characteristics of adolescent girls with different nutritional status / Efectos del programa de carrera de resistencia aeróbica en las características morfológicas de las adolescentes con diferentes estados nutricionales

SUMMARY: This study aimed to explore the effects of a single moderate-intensity aerobic endurance running program on the morphological characteristics of normal-weighted and overweighted female adolescents and whether effects differ between individuals of different nutritional statuses. A total of 47 adolescent girls participated in this randomized controlled trial. Before and after 12 weeks of intervention, measurements were obtained for body height, body mass, BMI, triceps, subscapular, abdominal, thigh, and calf skinfolds, and chest, abdominal, thigh, and calf circumference. The total duration of the program was 12 weeks, with a frequency of 2 hours/week (24 sessions). The individual session lasted 60 minutes, and the intensity ranged from 60 % HRmax to 80 %. The findings from the present study suggest that the 12-week aerobic endurance running program induced changes in morphological characteristics of female adolescents. The significant reductions in body mass and BMI were small for normal-weight adolescents (-2,64 % and -3,48 %) and moderate for overweight adolescents (-4,14 % and -4,36 %) following the experimental program. The magnitude of reductions in the skinfold thickness was small for both groups (triceps, subscapular, abdominal, and calf) and moderate for thigh skinfold and a sum of skinfolds in the overweight group. The reductions in the magnitude of all circular measures were small for both groups. It ranged from - 1.59 % to -2.59 % for normal-weight and from -2.54 % to -3.92 % for overweight adolescents, respectively. Additionally, the effects of the applied program seem more favorable to overweight than normal-weight adolescents. This study's current findings indicate that the 12-week aerobic endurance running program is effective due to improvements in morphological characteristics, body mass, and BMI of female adolescents. Additionally, this study's findings show that applied aerobic endurance running program proved more effective for overweight adolescents.

RESUMEN: Este estudio tuvo como objetivo explorar los efectos de un programa único de carrera de resistencia aeróbica de intensidad moderada sobre las características morfológicas de mujeres adolescentes con peso normal y con sobrepeso y si los efectos difieren entre individuos con diferentes estados nutricionales. Un total de 47 niñas adolescentes participaron en este ensayo controlado aleatorio. Antes y después de 12 semanas de intervención, se obtuvieron mediciones de altura corporal, masa corporal, IMC, tríceps, pliegues cutáneos subescapular, abdominal, muslo y pantorrilla, y circunferencia torácica, abdominal, muslo y pantorrilla. La duración total del programa fue de12 semanas, con una frecuencia de 2 horas/semana (24 sesiones). La sesión individual tuvo una duración de 60 minutos y la intensidad osciló entre el 60 % y el 80 % de la FCmáx. Los hallazgos del presente estudio sugieren que el programa de carrera de resistencia aeróbica de 12 semanas indujo cambios en las características morfológicas de las adolescentes. Las reducciones significativas en la masa corporal y el IMC fueron menores para los adolescentes con peso normal (-2,64 % y -3,48 %) y moderadas para los adolescentes con sobrepeso (-4,14 % y -4,36 %) después del programa experimental. La magnitud de las reducciones en el grosor del pliegue cutáneo fue pequeña para ambos grupos (tríceps, subescapular, abdominal y pantorrilla) y moderada para el pliegue cutáneo del muslo y la suma de los pliegues cutáneos en el grupo con sobrepeso. Las reducciones en la magnitud de todas las medidas circulares fueron pequeñas para ambos grupos. Osciló entre -1,59 % y -2,59 % para normopeso y entre -2,54 % y -3,92 % para adolescentes con sobrepeso, respectivamente. Además, los efectos del programa aplicado parecen más favorables para los adolescentes con sobrepeso que para aquellos de peso normal. Los hallazgos actuales de este estudio indican que el programa de carreras de resistencia aeróbica de 12 semanas es eficaz, debido a las mejoras en las características morfológicas, la masa corporal y el IMC de las adolescentes. Además, los hallazgos de este estudio muestran que el programa de carrera de resistencia aeróbica aplicada demostró ser más efectivo para los adolescentes con sobrepeso.

The Association Between Level of Physical Activity and Body Mass Index, and Quality of Life Among Elderly Women.

The process of aging leads to changes in functional abilities, fitness levels, level of physical activity, and body mass index (BMI), all of which causes changes in the quality of life. The current study aims to determine the association between the level of physical activity (PA) and BMI, and quality of life (QoL) among elderly women. The total sample numbered 156 women, with an average age of 67.7 ± 5.6 years. To determine the level of physical activity, the self-reported International Physical Activity Questionnaire Long Form (IPAQ-LF), was used. To calculate the values of the BMI, the standard procedure recommended by the World Health Organization was used. Quality of life was evaluated using the short form of the WHOQOL-BREF questionnaire designed by the World Health Organization. All the data were processed using the statistical package for data analysis SPSS 20.0. Pearson's correlation analysis shows statistically significant relations at the level of p < 0.01 between PA and Physical health in Housework = 0.36, Leisure time PA = 0.27, Walking = 0.24, Moderate PA 0.43, Total PA = 0.43, while the correlations between the variables at the significance level of p < 0.05 were determined in PA in transportation = 0.19 and High-intensity PA = 0.16. Multiple linear regression analysis of different levels of PA as independent variables on individual domains of QoL shows that there is an association of PA and Physical health (Sig = 0.000), more precisely, Total PA is statistically the most closely related to Physical health (Sig = 0.000), and then follows PA at work and Social relations (Sig = 0.036). Similar results were obtained when BMI is added to model A. In contrast to model A, model B shows a statistically significant association between PA and BMI with the environmental domain of QoL (Sig = 0.001). The results of the current study indicate that high- and moderate-intensity physical activity both have benefits for physical health, whereas moderate PA showed higher significance levels. Results also show that elderly women with higher BMI values achieve better results in the environmental domain of QoL.

The Role of Personality in Prediction of Satisfaction With Life in Recreational Athletes During the First Wave of Pandemic Covid-19.

The aim of this research is to contribute to the understanding of the concept of satisfaction with life by determining the relationship between personality traits and the subjective experience of satisfaction with life in students-recreational athletes. This research is based on the biological theory of personality by Hans Eysenck and it attempts to offer explanations of a possible change in satisfaction with life in the period of great social deprivation caused by the Covid-19 pandemic. The sample of subjects consisted of 120 undergraduate students (N = 120) of all years and both sexes, 55 (45.8%) males and 65 (54.2%) females, at the Faculty of Sport and Physical Education, the University of Nis. The average age of the subjects was 23.63 years (SD = 2.070). Eysenck's personality questionnaire (Eysenck Personality Questionnaire, EPQ: Eysenck et al., 1885, adapted and translated by Sipka, 1985) was used for the operationalization of personality structure. The SWLS scale (Satisfaction With Life Scale, Diener et al., 1985) was used for estimating satisfaction with life. A significant regression model, which explains 11% of variance in the subjective experience of satisfaction with life in recreational athletes, was obtained. In the model, extraversion stands out as a significant predictor from the group of personality traits (ß = 0.279). Neuroticism (ß = -0.160) and psychoticism (ß = -0.122) did not prove to be significant predictors of satisfaction with life in the structural model regardless of there being a significant negative correlation between neuroticism and satisfaction with life. The more extraverted participants had a keener subjective sense of satisfaction with life.

A lung area estimation method for analysis of ventilation inhomogeneity based on electrical impedance tomography.

PURPOSE: To evaluate a novel method for lung area estimation (LAE method) in electrical impedance tomography (EIT) images as a prerequisite of quantitative analysis of ventilation inhomogeneity. METHODS: The LAE method mirrors the lung regions in the functional EIT (fEIT) image and subsequently subtracts the cardiac related areas. In this preliminary study, 51 mechanically ventilated patients were investigated, including 39~patients scheduled for thoracic surgery (test group); 10 patients scheduled for orthopedic surgery without pulmonary disease (control group) and 2 ICU patients undergoing chest computed tomography (CT) examination. EIT data was recorded in all groups. The results of the LAE method were compared to those obtained with the fEIT method and to CT images. RESULTS: The lung area size determined with fEIT in control group is S(C,fEIT) = 361 +/- 35 (mean +/- SD) and in test group S(T,fEIT) = 299 +/- 61 (p< 0.01). The sizes estimated with the LAE method in control group S(C,LAE) = 353 +/- 27 and in test group S(T,LAE) = 353 +/- 61 (p=0.41). The result demonstrates that the novel LAE method improves the identification of lung region in EIT images, from which the analysis of ventilation distribution will benefit. The preliminary comparison with CT images exemplary indicates a closer match of the lung area shapes after the LAE than after the fEIT-based analysis. CONCLUSION: The LAE method is a robust lung area determination method, suitable for patients with healthy or seriously injured lungs.