RESUMO
PURPOSE: The impact of cataract maturity on the aqueous humor (AH) oxidant/antioxidant balance is largely controversial. This study was aimed at assessing the relationships between cataract maturity and AH lipid peroxidation markers and enzymatic antioxidants. PATIENTS AND METHODS: The concentrations of conjugated dienes (CD), lipofuscin-like fluorescent end-products (LLF), soluble proteins, as well as the activities of superoxide dismutase (SOD) and catalase (CAT) were measured in AH samples from nondiabetic patients with either immature (n=15) or mature (n=15) cataract. RESULTS: In the overall AH sample, the mean values of CD, LLF, SOD, and CAT were 0.160 ± 0.024 (OD234), 166 ± 27 RFU, 24.5 ± 7.1 U/ml, and 31.9 ± 3.9 pmol/ml, respectively. CD was positively correlated with SOD (r=0.647; P<0.001), CAT (r=-0.394; P=0.031), and LLF (r=-0.399; P=0.029). The LLF was negatively correlated with SOD (r=-0.461; P=0.010). In samples adjusted for confounding factors, differences between immature and mature cataract groups regarding SOD, CD, LLF, and total proteins were significant (P<0.05; for all variables). The multiple logistic regression analysis identified LLF (OR=4.08; P=0.038) and SOD (OR=4.99; P=0.031) as independent predictors of cataract maturity. CONCLUSIONS: These results suggest that AH lipid peroxidation markers and antioxidants may significantly depend on the cataract maturity stage.
Assuntos
Humor Aquoso/enzimologia , Biomarcadores/metabolismo , Catalase/metabolismo , Catarata/patologia , Peroxidação de Lipídeos , Peróxidos Lipídicos/metabolismo , Superóxido Dismutase/metabolismo , Idoso , Idoso de 80 Anos ou mais , Envelhecimento/fisiologia , Antioxidantes/metabolismo , Feminino , Humanos , Lipofuscina/metabolismo , Masculino , Pessoa de Meia-Idade , Oxirredução , Estresse OxidativoAssuntos
Infecções Estreptocócicas/complicações , Uveíte Anterior/etiologia , Doença Aguda , Adolescente , Adulto , Antiestreptolisina/sangue , Humanos , Iridociclite/etiologia , Iridociclite/imunologia , Iridociclite/microbiologia , Masculino , Faringite/complicações , Infecções Estreptocócicas/imunologia , Infecções Estreptocócicas/microbiologia , Streptococcus/patogenicidade , Tonsilite/complicações , Uveíte Anterior/imunologia , Uveíte Anterior/microbiologiaRESUMO
PURPOSE: To report a rare case of tuberculosis with facial abscess. METHODS: A 4 1/2-year-old girl had an acute left upper eyelid abscess and a large, spherical tumescence involving the right upper eyelid, eyebrow, and forehead. The left upper eyelid abscess was drained, and the mass involving the right eyelid, eyebrow, and forehead was excised. RESULTS: Histopathologic and microbiologic examination established a human type of tuberculous mycobacterium as the cause of the bilateral facial lesions. CONCLUSION: Tuberculosis should be considered as a possible cause of abscess even when clinical features are not typical.
