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Clin Cardiol ; 46(8): 877-885, 2023 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-37417371

RESUMO

Drug-coated balloons (DCBs) have been used in dialysis patients with arteriovenous fistula (AVF) stenosis, but whether DCBs have advantages over ordinary balloons is still controversial. A meta-analysis was designed to investigate the safety and efficacy of DCBs and common balloons (CBs) in the treatment of AVF stenosis. We searched the PubMed, EMBASE, and China National Knowledge Internet (CNKI) databases for randomized controlled trials that evaluated the comparison of DCB angioplasty versus CB angioplasty for AVF stenosis in dialysis patients and reported at least one outcome of interest. The results showed that the DCB group had a higher first-stage patency rate of the target lesion 6 months [odds ratio, OR = 2.31, 95% confidence interval, CI: (1.69, 3.15), p < .01] and 12 months [OR = 2.09, 95% CI: (1.50, 2.91), p < .01] after surgery. There was no statistically significant difference in all-cause mortality between the two groups at 6 months [OR = 0.85, 95% CI: (0.47, 1.52), p = .58] and 12 months [OR = 0.99, 95% CI: (0.60, 1.64), p = .97]. Compared with CB, DCBs as a new endovascular treatment for AVF stenosis have a higher primary patency rate of target lesions and can delay the occurrence of restenosis. There is no evidence that DCB can increase the mortality of patients.


Assuntos
Angioplastia com Balão , Fístula Arteriovenosa , Humanos , Grau de Desobstrução Vascular , Oclusão de Enxerto Vascular/diagnóstico , Oclusão de Enxerto Vascular/etiologia , Oclusão de Enxerto Vascular/terapia , Constrição Patológica/complicações , Resultado do Tratamento , Materiais Revestidos Biocompatíveis , Fatores de Tempo , Angioplastia com Balão/efeitos adversos , Angioplastia com Balão/métodos , Fístula Arteriovenosa/diagnóstico , Fístula Arteriovenosa/terapia , Fístula Arteriovenosa/complicações , Paclitaxel
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