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1.
Europace ; 23(23 Suppl 1): i96-i104, 2021 03 04.
Artigo em Inglês | MEDLINE | ID: mdl-33751086

RESUMO

AIMS: This work aims at presenting a fully coupled approach for the numerical solution of contact problems between multiple elastic structures immersed in a fluid flow. The key features of the computational model are (i) a fully coupled fluid-structure interaction with contact, (ii) the use of a fibre-reinforced material for the leaflets, (iii) a stent, and (iv) a compliant aortic root. METHODS AND RESULTS: The computational model takes inspiration from the immersed boundary techniques and allows the numerical simulation of the blood-tissue interaction of bioprosthetic heart valves (BHVs) as well as the contact among the leaflets. First, we present pure mechanical simulations, where blood is neglected, to assess the performance of different material properties and valve designs. Secondly, fully coupled fluid-structure interaction simulations are employed to analyse the combination of haemodynamic and mechanical characteristics. The isotropic leaflet tissue experiences high-stress values compared to the fibre-reinforced material model. Moreover, elongated leaflets show a stress concentration close to the base of the stent. We observe a fully developed flow at the systolic stage of the heartbeat. On the other hand, flow recirculation appears along the aortic wall during diastole. CONCLUSION: The presented FSI approach can be used for analysing the mechanical and haemodynamic performance of a BHV. Our study suggests that stresses concentrate in the regions where leaflets are attached to the stent and in the portion of the aortic root where the BHV is placed. The results from this study may inspire new BHV designs that can provide a better stress distribution.


Assuntos
Valva Aórtica , Próteses Valvulares Cardíacas , Valva Aórtica/cirurgia , Simulação por Computador , Hemodinâmica , Humanos , Modelos Cardiovasculares , Estresse Mecânico
2.
CCF Trans High Perform Comput ; 3(4): 407-426, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34993419

RESUMO

Non-linear phase field models are increasingly used for the simulation of fracture propagation problems. The numerical simulation of fracture networks of realistic size requires the efficient parallel solution of large coupled non-linear systems. Although in principle efficient iterative multi-level methods for these types of problems are available, they are not widely used in practice due to the complexity of their parallel implementation. Here, we present Utopia, which is an open-source C++ library for parallel non-linear multilevel solution strategies. Utopia provides the advantages of high-level programming interfaces while at the same time a framework to access low-level data-structures without breaking code encapsulation. Complex numerical procedures can be expressed with few lines of code, and evaluated by different implementations, libraries, or computing hardware. In this paper, we investigate the parallel performance of our implementation of the recursive multilevel trust-region (RMTR) method based on the Utopia library. RMTR is a globally convergent multilevel solution strategy designed to solve non-convex constrained minimization problems. In particular, we solve pressure-induced phase-field fracture propagation in large and complex fracture networks. Solving such problems is deemed challenging even for a few fractures, however, here we are considering networks of realistic size with up to 1000 fractures.

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