RESUMO
A clinical case with a rare dermatosis of children, papillary pigmented dystrophy of the skin, is reported. Clinical and morphological picture of the disease is fairly typical and is not difficult to diagnose; however since the condition is very rare, it is often misdiagnosed. This dermatosis runs a benign course in children, but the patients should be followed up on an outpatient basis.
Assuntos
Acantose Nigricans/patologia , Acantose Nigricans/diagnóstico , Axila , Biópsia , Criança , Feminino , Humanos , Pele/patologiaRESUMO
Basing on the WHO recommendations and on the statistical classification of diseases in the USSR (Section 691) on the use of the 'atopic dermatitis' term, the author thinks it desirable that age-associated features of the disease and clinical symptoms be taken into consideration and that the diagnosis be worded as 'atopic dermatitis' at the stage of childhood eczema or diffuse or local neurodermatitis; atopic neurodermatitis should also be considered as a rightful term.
Assuntos
Dermatite Atópica/patologia , Eczema/patologia , Criança , Humanos , Terminologia como Assunto , U.R.S.S.RESUMO
Structural changes in the blood mononuclear glycocalyx has been revealed in children suffering from neurodermatitis. These shifts correlated with the cellular ability to respond to mitogenic stimulation. Treatment by UV-irradiated blood autotransfusions normalized the structure and function of mononuclears whereas routine therapy has been ineffective.
Assuntos
Transfusão de Sangue Autóloga , Sangue/efeitos da radiação , Leucócitos Mononucleares/patologia , Neurodermatite/terapia , Raios Ultravioleta , Adolescente , Criança , Humanos , Neurodermatite/patologiaRESUMO
In children suffering from chronic dermatoses (psoriasis and neurodermatitis), the glycocalix of blood mononuclears displays an Alcian blue dye sorption by 23-25% less than that in healthy children. The UV irradiation of their blood (254 nm), in addition to a course of UV-irradiated blood autotransfusion, resulted in an elevated sorption capacity of the mononuclear glycocalix up to the normal. A possible involvement of these changes in immunocompetent cell glycocalix in the pathogenesis of chronic dermatoses is discussed, as well as the significance of glycocalix normalization in the medicinal effect of UV-irradiated blood autotransfusion.