[Effect of experimental herpesvirus infection on morphofunctional state of mast cells]. / Vliianie éksperimental'no'i gerpesvirusno'i infektsii na morfofunk tsional'noe sostoianie tuchnykh kletok.

Mast cells are involved in the reaction of the organism to herpesvirus infection, which manifests by changes in their count, morphology, and function. The onset of infection is characterized by primary activation of mast cells, the peak of disease by suppressed function, and convalescence by secondary activation and stabilization of cell morphology and function. Viral infection running in the presence of immunosuppression caused by cyclophosphamide is characterized by deep persistent suppression of the morphology and functions of mast cells at the peak of disease.

[The effect of different infectious agents on the intensification of hematopoiesis during immunosuppression]. / Vliianie razlichnykh infektsionnykh agentov na usilenie krovetvoreniia v usloviiakh immunosupressii.

The action of Staphylococcus aureus, Escherichia coli and Herpes simplex virus on the hemopoiesis of mice with cytostatic myelosuppression was studied. The study revealed that the infection of the animals simultaneously with the action of cyclophosphamide considerably activated the processes leading to the restoration of hemopoiesis due to an increase in the mitotic activity of hemopoietic cells, the accelerated differentiation of hemopoietic precursor cells which could survive the cytostatic action and an increase in the functional activity of the hemopoiesis-producing microenvironment.