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1.
Cardiovasc Intervent Radiol ; 46(11): 1571-1580, 2023 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-37580422

RESUMO

PURPOSE: Mechanical thrombectomy for the treatment of deep vein thrombosis (DVT) is being increasingly utilized to reduce symptoms and prevent postthrombotic syndrome (PTS), but more data on clinical outcomes are needed. Mechanical thrombectomy was studied in the ClotTriever Outcomes (CLOUT) registry with 6-month full analysis outcomes reported herein. MATERIALS AND METHODS: The CLOUT registry is a prospective, all-comer study that enrolled 500 lower extremity DVT patients across 43 US sites treated with mechanical thrombectomy using the ClotTriever System. Core-lab assessed Marder scores and physician-assessed venous patency by duplex ultrasound, PTS assessment using Villalta score, venous symptom severity, pain, and quality of life scores through 6 months were analyzed. Adverse events were identified and independently adjudicated. RESULTS: All-cause mortality at 30 days was 0.9%, and 8.6% of subjects experienced a serious adverse event (SAE) within the first 30 days, 1 of which (0.2%) was device related. SAE rethrombosis/residual thrombus incidence was 4.8% at 30 days and 8.0% at 6 months. Between baseline and 6 months, venous flow increased from 27.2% to 92.5% of limbs (P < 0.0001), and venous compressibility improved from 28.0% to 91.8% (P < 0.0001), while median Villalta scores improved from 9.0 at baseline to 1.0 at 6 months (P < 0.0001). Significant improvements in venous symptom severity, pain, and quality of life were also demonstrated. Outcomes from iliofemoral and isolated femoral-popliteal segments showed similar improvements. CONCLUSION: Outcomes from the CLOUT study, a large prospective registry for DVT, indicate that mechanical thrombectomy is safe and demonstrates significant improvement in symptoms and health status through 6 months. Level of Evidence 3: Non-randomized controlled cohort/follow-up study.


Assuntos
Síndrome Pós-Trombótica , Trombose Venosa , Humanos , Trombectomia/efeitos adversos , Veia Femoral , Seguimentos , Qualidade de Vida , Veia Ilíaca , Resultado do Tratamento , Grau de Desobstrução Vascular , Trombose Venosa/diagnóstico por imagem , Trombose Venosa/terapia , Terapia Trombolítica/efeitos adversos
3.
Gastroenterology Res ; 12(3): 115-119, 2019 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-31236151

RESUMO

BACKGROUND: The aim of the study was to evaluate the safety and feasibility of ultrasound guidance gastric access for percutaneous retrograde transabdominal gastrostomy (G)-tube placement. METHODS: Twenty-eight patients undergoing 31 percutaneous retrograde transabdominal G-tube placements utilizing ultrasound-guided gastric accesses were retrospectively identified. RESULTS: All patients had successful placement of G tubes with ultrasound-guided gastric access. There were no cases of aspiration or peritonitis. Average fluoroscopy time was 2.7 ± 1.4 min and average radiation dose was 220 ± 202 µGym2. CONCLUSIONS: Ultrasound-guided access for gastrostomy placement is safe and feasible and can be performed with minimal fluoroscopy times resulting in low patient and operator radiation dose.

4.
Vasc Endovascular Surg ; 51(7): 491-492, 2017 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-28784055

RESUMO

Popliteal venous aneurysms (PVAs) are rare and may represent a cause of recurrent pulmonary embolism. We present a case of PVA identified on ultrasound for deep venous thrombosis in a 27-year-old female with popliteal fossa pain. We discuss our recommendations for treatment and present a review of the previously reported cases.


Assuntos
Aneurisma/diagnóstico por imagem , Veia Poplítea/diagnóstico por imagem , Ultrassonografia Doppler em Cores , Adulto , Dilatação Patológica , Feminino , Humanos , Valor Preditivo dos Testes
5.
J Vasc Access ; 18(3): 250-254, 2017 May 15.
Artigo em Inglês | MEDLINE | ID: mdl-28430314

RESUMO

PURPOSE: Transulnar access (TUA) has been shown to be an effective alternative to transradial access (TRA) for coronary intervention. This study evaluates the safety and efficacy of TUA in patients undergoing visceral interventions in the setting of contraindication to TRA. MATERIALS AND METHODS: Patients who underwent visceral interventions via ulnar approach were included in the study. Outcome variables include technical success, access site and bleeding complications. RESULTS: From May 2014 to September 2016, TUA was attempted 17 times in 14 patients (mean age: 60 years; range: 27 to 81 years) for whom TRA was planned for visceral intervention, but contraindicated. Contraindication to TRA included Barbeau D waveform (n = 3), radial artery diameter <2 mm (n = 8), known radial loop (n = 2), high takeoff of the radial artery (n = 2), prior radial artery occlusion (RAO) (n = 1), and radiocephalic arteriovenous fistula (n = 1). Interventions included selective internal radiation therapy (SIRT) (n = 4), SIRT mapping (n = 2), chemoembolization (n = 6), renal embolization (n = 1) and bland liver embolization (n = 4). Technical success was achieved in 94.1% (16/17 cases) with the single failure attributed to an inability to cannulate the target vessel due to vessel tortuosity, requiring ipsilateral femoral crossover. There were no major access site or bleeding complications. Minor adverse events include two access site hematomas, which were successfully treated with conservative management. CONCLUSIONS: TUA for visceral interventions is a safe and effective alternative to femoral approach when TRA is contraindicated.


Assuntos
Cateterismo Periférico/métodos , Procedimentos Endovasculares/métodos , Artéria Radial/diagnóstico por imagem , Artéria Ulnar/diagnóstico por imagem , Adulto , Idoso , Idoso de 80 Anos ou mais , Cateterismo Periférico/efeitos adversos , Procedimentos Endovasculares/efeitos adversos , Estudos de Viabilidade , Feminino , Hematoma/etiologia , Hemorragia/etiologia , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Resultado do Tratamento
6.
Clin Imaging ; 43: 106-109, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-28278445

RESUMO

PURPOSE: To evaluate the negative predictive power of computed tomography angiography (CTA) for the identification of obscure acute gastrointestinal (GI) bleeding (GI bleeding not visualized/treated by endoscopy) on subsequent mesenteric angiography (MA) with the intention to treat. MATERIALS AND METHODS: A retrospective chart review of patients was performed who underwent mesenteric angiography for the evaluation/treatment of acute GI bleeding between November 2012 and July 2016. Patients with negative CTA examinations that proceeded to MA were identified. Negative predictive value (NPV) was calculated. RESULTS: 20 patients (14 male, 6 female; average age: 73.1±12.8years) underwent 20 negative CTA examinations for the evaluation and treatment of GI bleeding followed by mesenteric angiography. Eighteen of 20 patients had negative subsequent MA (negative predictive value, NPV=90%). Both false negative cases were upper GI bleed (vs 0 lower GI bleed); this difference was significant (p<0.05). CONCLUSIONS: The high NPV of CTA for the evaluation of GI bleeding suggests utility for excluding patients that are unlikely to benefit from MA and subsequent endovascular therapy. CTA may be considered for the first line diagnostic study for the evaluation of obscure GI bleeding.


Assuntos
Angiografia por Tomografia Computadorizada/métodos , Hemorragia Gastrointestinal/diagnóstico , Sangue Oculto , Doença Aguda , Adulto , Idoso , Idoso de 80 Anos ou mais , Angiografia/métodos , Catéteres , Endoscopia Gastrointestinal , Feminino , Fluoroscopia , Hemorragia Gastrointestinal/diagnóstico por imagem , Humanos , Masculino , Mesentério , Pessoa de Meia-Idade , Estudos Retrospectivos , Tomografia Computadorizada por Raios X/métodos
7.
Cardiovasc Intervent Radiol ; 40(2): 216-222, 2017 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-27882429

RESUMO

PURPOSE: Recurrent spontaneous hemarthrosis is an infrequent but debilitating late complication of joint replacement, affecting up to 1.6% of patients with arthroplasty of the affected joint. Repeated episodes of bleeding result in an inflammatory cascade that further propagates bleeding events. Open and arthroscopic synovectomy are often performed when conservative treatments fail. Transarterial embolization is increasingly utilized as a less invasive option; however, its role is not widely established. We performed a systematic literature review to report the safety and efficacy of transarterial embolization in treating recurrent hemarthrosis in the setting of prior arthroplasty. MATERIALS AND METHODS: A systematic review was conducted in accordance with the Preferred Reporting Items for Systematic Review and Meta-Analysis guidelines. A structured search was performed in PubMed, Web of Science, Embase, and SCOPUS databases of patients undergoing embolization for recurrent hemarthrosis after arthroplasty. Patients immediately post-operative, those embolized at first bleeding episode, and those with hemophilia were excluded. Demographic data, clinical information, angiographic findings, treatment, and outcomes were tabulated. RESULTS: The search identified 119 titles of which 24 were deemed relevant, comprising 91 patients undergoing 99 embolization procedures. Mean time from prosthesis implantation was 32.2 months. Technical success was 99%. Mean follow-up time was 24.9 months. There were 10 recurrences (10%). Two cases were complicated by joint infection requiring arthroplasty revision. CONCLUSIONS: Transarterial embolization for recurrent spontaneous hemarthrosis may be safe and effective in patients having undergone arthroplasty of the affected joint.


Assuntos
Artroplastia de Quadril/efeitos adversos , Artroplastia do Joelho/efeitos adversos , Embolização Terapêutica/métodos , Procedimentos Endovasculares/métodos , Hemartrose/terapia , Adulto , Idoso , Idoso de 80 Anos ou mais , Angiografia , Feminino , Hemartrose/diagnóstico por imagem , Hemartrose/etiologia , Humanos , Masculino , Pessoa de Meia-Idade , Recidiva
8.
Expert Rev Med Devices ; 7(1): 11-9, 2010 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-20021237

RESUMO

Permanent or temporary implantation of inferior vena cava filters for protection against pulmonary embolism is well established. There have been numerous devices developed for this purpose, each of which has proprietary design considerations that affect performance and potentially impose limitations with regard to positioning, efficacy and risk profile. This article describes a recently developed, unique inferior vena cava filter design that employs a separated filtration component and a novel double-ring anchoring system that allows intraprocedural capture and repositioning for optimized placement. In addition, early experience suggests easy removal when desired, a high rate of filtration success and excellent caval patency.


Assuntos
Embolia Pulmonar/prevenção & controle , Filtros de Veia Cava , Animais , Filtração/instrumentação , Humanos
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