Assuntos
Compostos de Benzalcônio/farmacologia , Túnica Conjuntiva/efeitos dos fármacos , Células Epiteliais/efeitos dos fármacos , Soluções Oftálmicas/farmacologia , Animais , Túnica Conjuntiva/fisiologia , Túnica Conjuntiva/ultraestrutura , Células Epiteliais/fisiologia , Células Epiteliais/ultraestrutura , Fluoresceínas/farmacocinética , Corantes Fluorescentes , Microscopia Eletrônica , Permeabilidade , CoelhosRESUMO
The mantle edge of the freshwater pulmonate snails Lymnaea stagnalis and Biomphalaria pfeifferi was investigated with histochemical and ultrastructural methods. The mantle edge gland, which is involved in shell formation, consists of the periostracal groove and the belt. This belt appears to be composed of various regions. In the area of the periostracal groove a number of subepithelial gland cell types occur; these release their products into the groove. Between the groove cells ciliated free nerve endings terminate; the corresponding perikarya occur in the subepidermal connective tissue. Also in the posterior belt region free nerve endings were observed between the epithelial cells; in addition, a particular type of subepithelial gland cell was found in this area. The epithelial cells of this part of the belt have the ultrastructural characteristics of ion and water transporting cells; they are probably involved in calcium deposition and resorption. The possible role of the free nerve endings and of the subepithelial gland cells is discussed.
