RESUMO
In the King Khalid University Hospital (Central Province) and King Fahad Hospital of the University (Eastern Province) Saudi Arabia, we identified 64 infants with cholestasis. The causes of cholestasis were idiopathic neonatal hepatitis in 29; extrahepatic biliary atresia in 17; neonatal hepatitis secondary to Rubella and Cytomegalovirus in six and four infants, respectively; paucity of intrahepatic bile ducts in six and galactosaemia in two. The diagnosis was confirmed by liver biopsy and or operative cholangiography, in all infants.
Assuntos
Colestase Extra-Hepática/epidemiologia , Colestase Intra-Hepática/epidemiologia , Idade de Início , Pré-Escolar , Colangiografia , Colestase Extra-Hepática/diagnóstico , Colestase Extra-Hepática/etiologia , Colestase Intra-Hepática/diagnóstico , Colestase Intra-Hepática/etiologia , Feminino , Humanos , Incidência , Masculino , Arábia Saudita/epidemiologiaRESUMO
OBJECTIVE: To report the first case of human infection (infective endocarditis [IE]) caused by Pasteurella gallinarum and to review the literature regarding IE caused by the genus Pasteurella. SETTING: University hospital based. PATIENT: An adolescent boy who underwent successful correction for truncus arteriosus 10 years before the present illness. RESULTS: Persistent fever, pallor, and a palpable spleen suggested IE clinically. Echocardiography documented vegetation in the conduit that was used for surgical correction. Blood cultures grew P. gallinarum and confirmed its role as the causative organism for IE in the patient. CONCLUSION: This case illustrates that IE may develop in a child with congenital heart disease several years after surgical intervention using material that is foreign to the body (conduit), and that such a complication may involve unusual pathogens. These observations emphasize the need for careful long-term follow-up of children with congenital heart disease even after successful surgical correction.
Assuntos
Endocardite Bacteriana/microbiologia , Infecções por Pasteurella/microbiologia , Pasteurella , Persistência do Tronco Arterial/cirurgia , Técnicas de Tipagem Bacteriana , Prótese Vascular , Criança , Humanos , Masculino , Pasteurella/classificação , Pasteurella/isolamento & purificação , Complicações Pós-Operatórias/microbiologiaRESUMO
During the four years period from 1988 to 1991, 50 pediatric patients were diagnosed to have bacterial meningitis, out of a total number of 9057 pediatric admissions at Qatif Central Hospital, Qatif, Saudi Arabia, and 82% were less than two years of age. The causative organisms were isolated in 27 (54%) patients. The bacteria grown included Haemophilus influenzae type B in 8 patients (29.6%), Neisseria meningitidis in 8 patients (29.6%), Streptococcus pneumonia in 6 (22%) patients, and other bacteria in 5 patients (18.5%). Cerebro spinal fluid cultures from twenty three patients (46%) showed no organisms, however their clinical and C.S.F. findings were compatible with bacterial meningitis. One case of H. influenzae type B was resistant to ampicillin. Six patients died with an over all mortality of 12%, and 10 patients (20%) developed some kind of C.N.S. sequelae. Partially treated meningitis formed a large percentage of our sample.
