Physiological and Performance Impacts After Field Supramaximal High-Intensity Interval Training With Different Work-Recovery Duration.

High-intensity interval training (HIIT) has numerous external load control variables. The management of these variables makes the physiological responses and performance presented by athletes also modify. The present study aimed to assess the activity of CK and LDH enzymes, performance and metabolic responses caused by two HIIT protocols above the maximum in male recreational runners. Fifteen recreational male runners performed two HIIT protocols in randomized order with multiple conditions: 1) H15 (n = 15), with a HIIT protocol of 15:15 work-recovery duration, and 2) H30 (n = 15) with a HIIT protocol of 30:30 work-recovery duration. Both protocols were performed at similar intensity (130% vV̇O2 max ), one set until voluntary exhaustion. Blood samples were collected and used to capture the levels and activities of blood lactate (BLac: mmol⋅L-1), glucose (GLU: mg⋅dL-1), creatine kinase (CK: U⋅L-1), and lactate dehydrogenase (LDH: U⋅L-1). BLac and GLU were collected at pre, five, and ten minutes after the H15 and H30 protocols were performed. Blood samples were used to measure the activities of CK and LDH enzymes, which were verified 24 h before and 48 h after the protocols. The distance traveled (m), total time (s), and bouts performed (rep) were also registered. Significant differences between conditions H15 and H30 were observed in the bouts performed (p = 0.001; ES = 1.19). Several statistical differences were found over time for BLac [pre vs. post 5 (both conditions: p = 0.001), pre vs. post 10 (both conditions: p = 0.001), and post 5 vs. post 10 (H30: p = 0.004)], CK [pre vs. post 24 (H15: p < 0.001; ES = 0.97 and H30: p = 0.001; ES = 0.74) post 24 vs. post 48 (H30: p = 0.03; ES = 0.56)], and LDH [pre vs. post24 (H15: p = 0.008; ES = 1.07 and H30: p = 0.022; ES = 0.85). No statistical differences between conditions were observed for any blood parameter. Thus, the volunteers exhibited equal performance in both protocols, which resulted in a similar physiological response. Despite this similarity, in comparison to H15, the H30 protocol presented lower CK activity post 48 and lactate levels after 10 min post protocol.

Influence of different respiratory maneuvers on exercise-induced cardiac vagal inhibition.

Physical exercise inhibits cardiac vagal activity. To study the relationship between heart rate (HR) and respiratory pattern, we applied the 4-s exercise test (4sET) and measured cardiac vagal index (CVI) in 30 healthy subjects who served as their own controls, using the standard plus three additional variations, essentially respiratory, of the original protocol: (a) a maximum inspiratory apnea of 16 s, of which 8 s were in the pre-exercise phase (4sET(insp)); (b) free respiratory pattern (4sET(unc)); and (c) maximum expiratory apnea of 12 s (4sET(exp)). The respective results were expressed by the following CVIs: CVI(insp), CVI(unc) and CVI(exp). CVI was determined in a continuous digital ECG recording through a specific ratio of two RR interval durations. The results [(mean +/- SEM)] for the four different maneuvers were as follows: CVI (1.56 +/- 0.05), CVI(insp) (1.55 +/- 0.05), CVI(unc) (1.63 +/- 0.05) and CVI(exp) (1.37 +/- 0.02). ANOVA-Bonferroni significant differences were only found between CVI(exp) and CVI(insp) (P = 0.009), CVI(unc) (P < 0.001) and CVI (P = 0.003). Dividing our sample in terciles according to CVI values, those with lower CVI, showed an attenuation of biphasic HR response after a 15 s maximum inspiratory apnea. We conclude that cardiac vagal reflex seems to be influencing the biphasic HR response modulation after a 12 s inspiratory apnea as described in the original protocol of 4sET, and this appears to be the option that best discriminates the cardiac vagal reflex, with less variability in the maneuvers when subjects are divided in terciles.

Initial and final exercise heart rate transients: influence of gender, aerobic fitness, and clinical status.

STUDY OBJECTIVES: To compare the independent and additive data provided by initial and final heart rate (HR) exercise transients, and to analyze both according to gender, aerobic fitness, clinical status, and medication usage. DESIGN: Retrospective study. SETTING: Exercise medicine clinic. PATIENTS: A total of 544 subjects (363 men) with a mean (+/- SD) age of 50 +/- 14 years (age range, 10 to 91 years), including asymptomatic and coronary artery disease patients. MEASUREMENTS AND RESULTS: HR transients were obtained from the following two exercise protocols: 4-s exercise test (4sET) followed by a maximal cardiopulmonary cycling exercise test (CPET). The initial HR transient was represented by the cardiac vagal index (CVI), which was obtained by the 4sET, and the final transient (ie, HR recovery [HRR]) was determined by the following equation: CPET maximal HR - the 1-min postexercise HR. Transients were modestly related (r = 0.22; p < 0.001) when adjusted for age, aerobic fitness, clinical status, and negative chronotropic action drug usage. The transients were unrelated to gender (vs CVI, p = 0.10; vs HRR, p = 0.15). Subjects with a measured maximum oxygen uptake (VO2max) exceeding 100% of the predicted maximal aerobic power showed higher CVIs than those in less aerobically fit subjects (VO2max < 50% subgroup, p = 0.009; VO2max < 75% subgroup, p = 0.034). Both transient results differed for asymptomatic and cardiac subjects (CVI, 1.32 +/- 0.02 vs 1.42 +/- 0.02, respectively [p = 0.001]; HRR, 33 +/- 1 beats/min (bpm) vs 37 +/- 1 bpm, respectively [p = 0.009]). CONCLUSIONS: The initial and final HR transients were modestly related, suggesting a potentially complementary clinical role for both measurements in the assessment of autonomic function in patients with coronary artery disease. Although both HR transients tended to behave similarly under the influence of several variables, the initial HR transient, measured during 4sET, was more likely to discriminate distinct subgroups compared with the final HR transient.