Assuntos
Síndrome de Chediak-Higashi/epidemiologia , Cabelo/patologia , Pele/patologia , Negro ou Afro-Americano , População Negra , Síndrome de Chediak-Higashi/imunologia , Quimiotaxia de Leucócito , Humanos , Lactente , Ativação Linfocitária , Masculino , Neutrófilos/imunologia , Fagocitose , África do Sul , Espectrofotometria/métodosRESUMO
Necrobiosis lipoidica of the legs, in which deep ulcers resembling erythema induratum, gummas or a variety of other chronic progressive ulcerating skin diseases occur, is described. In 2 cases the lesions were precipitated by a crush injury elsewhere in the same leg, but not at the site of the ultimate lesions. In 2 further pairs of siblings the same problem arose as a familial complaint without trauma. These cases were distinguished by severe necrosis in the absence of diabetes.
Assuntos
Úlcera da Perna/patologia , Necrobiose Lipoídica/genética , Adulto , Feminino , Humanos , Úlcera da Perna/genética , Masculino , Pessoa de Meia-Idade , Necrobiose Lipoídica/etiologia , Necrobiose Lipoídica/patologia , Fatores de TempoRESUMO
Subcutaneous phycomycosis in a Black child is reported, together with clinical, histological and mycological studies. This is the first case, to our knowledge, to be identified mycologically in South Africa. Oral potassium iodide gave an excellent therapeutic result.
Assuntos
Dermatomicoses/microbiologia , Pré-Escolar , Dermatomicoses/epidemiologia , Feminino , Fungos/isolamento & purificação , Humanos , África do SulRESUMO
The type of skin reactions which occur in commerce and industry and the causal agents are summarized.
Assuntos
Dermatite de Contato/etiologia , Dermatite Ocupacional/etiologia , Cromatos/efeitos adversos , Dermatite de Contato/diagnóstico , Humanos , Fenômenos Fisiológicos da PeleRESUMO
Attention is drawn to the widespread use of bleaching preparations by Black women. These products often contain hydroquinone. They act efficiently as bleaching agents, but chronic oversaturation of the skin with hydroquinone eventually produces ochronosis. This complication has reached epidemic proportions in the Transvaal. Although the assay of hydroquinone in cosmetic products has not yet been standardized, we present some provisional results. The clinical, social and industrial aspects are also significant.
Assuntos
Cosméticos/intoxicação , Hidroquinonas/intoxicação , Ocronose/induzido quimicamente , Negro ou Afro-Americano , População Negra , Doença Crônica , Cosméticos/análise , Face , Feminino , Humanos , Hidroquinonas/análise , Métodos , África do SulRESUMO
Although freely available, topical nitrofurazone (Furacin) frequently causes severe contact dermatitis, necessitating hospitalization. Six patients with sensitivity reactions to topical nitrofurazone are described. Our experience suggests that the free availability of this drug may increase the incidence of reactions due to its use, and should be condemned.