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Neurophysiol Clin ; 21(5-6): 449-58, 1991 Dec.
Artigo em Francês | MEDLINE | ID: mdl-1808503

RESUMO

Latencies, amplitudes and localization of the maximum of the peaks of late onset evoked responses have been studied in 3 groups of elderly people: normal, depressed and demented (probable dementia of Alzheimer type DAT) at the early stage of the disease. Evoked responses with an auditory oddball paradigm have been recorded with 16 electrodes in 2 situations: counting the target sounds, and motor response with measurement of the reaction time. No difference in amplitude was observed between the 3 groups. Only a significant difference for P3 latency was observed between the DAT and the depressed groups and only in the counting situation. The maximum P3 response was most often found on the anterior areas in the DAT group and in the posterior areas in the normal and depressed groups. The topographic localization of the P3 peak could therefore be of some help in the characterize of subjects with probable DAT at the early stage of the disease.


Assuntos
Doença de Alzheimer/fisiopatologia , Mapeamento Encefálico , Encéfalo/fisiopatologia , Transtorno Depressivo/fisiopatologia , Idoso , Idoso de 80 Anos ou mais , Análise de Variância , Eletroencefalografia , Potenciais Evocados/fisiologia , Humanos , Pessoa de Meia-Idade , Tempo de Reação/fisiologia
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