[Radiological study of metaphyso-epiphyseal anomalies in osteogenesis imperfecta. Apropos of 61 cases]. / Etude radiologique des anomalies métaphyso-épiphysaires dans l'ostéogenèse imparfaite. A propos de 61 observations.

The object of the present study was to examine all the metaphyseal and epiphysial abnormalities from sixty one patients with osteogenesis imperfecta. Regarding the growing ends of the bones, eight of the 61 children (13%) had disorders in the epiphyseal ends of the bones. The development of the radiological features can be divided into three stages. The last one is characterized by a severe epiphyseal deformation. Histologically there is a disorderly proliferation of the calcified cartilage at the center of the epiphyses. Several physio-pathological hypothesis may be advanced, and particularly the responsibility of the vascular upsets secondary to fractures.

[Radiological study of epiphyseal abnormalities in osteogenesis imperfecta. Apropos of 61 cases]. / Etude radiologique des anomalies épiphysaires dans l'ostéogénèse imparfaite. A propos de 61 observations.

Sixty-one cases of osteogenesis imperfecta were studied to try to discover the cause of metaphyseal and epiphyseal deformities. These deformities were noticeable in 8 cases out of 61 at the level of the upper and lower end of the femur in all cases and sometimes at the level of the lower end of the tibia and the upper end of the humerus. Several grades are described: First grade - protrusion of the growth plate into the epiphysis. Second grade - disorganization of the architecture of the epiphysis. Third grade - major deformity. It seems that the deformities are secondary to lesions of the growth plates. Several hypotheses are suggested. The authors consider that the main role is played by segmental fractures creating areas of ischemia in the epiphyses.

[A study of changes in bone mineral content in relation to age, using Cameron's method (author's transl)]. / Variation du contenu minéral osseux en fonction de l'âge. Etude par la méthode de Cameron.

The amounts of calcium present in the skeleton were accurately measured and monitored in 1280 women and 418 men, using Cameron's photon absorption method of bone mineral content measurement. Used as a screening test on the first visit, this method becomes an excellent means of longitudinal surveillance after assessment of the calcium/phosphorus balance.