Evaluation of sclerotherapy of benign oral vascular lesions with monoethanolamine oleate.

OBJECTIVE: To investigate the efficacy of sclerotherapy with monoethanolamine oleate (MEO) in a series of cases of benign oral vascular lesions (BOVL). MATERIAL AND METHODS: Clinical records and images were retrieved (2015-2019), and data regarding age, gender, location, size, symptomatology, treatment and outcomes of patients were collected. All patients were diagnosed according to the classification of International Society for the Study of Vascular Anomalies and received the same treatment protocol (MEO 0.05 g/mL). The collected data were submitted to descriptive analysis and Pearson's chi-square test (p ≤ 0.05). RESULTS: Thirty-seven patients were treated. Most were female (70.3%) aged 9 to 88 years (median, 57.5 ± 17.4 years). Lower lip (54.1%) was the most affected site followed by buccal mucosa (16.2%). Thirty-two lesions were asymptomatic and 35.1% showed ≤ 0.5 cm in size. In 48.6% of the patients, only one application of MEO was performed. Complete regression occurred in 62.2% of cases, whereas 27% showed partial regression. One patient showed hypersensitivity during treatment. There was no significant difference between clinical outcome and age, anatomic site, size, and number of applications of MEO. CONCLUSIONS: Sclerotherapy with MEO is an acceptable and affordable treatment and can provide satisfactory results in BOVL, especially where other treatment options could compromise the esthetic aspects. CLINICAL RELEVANCE: As it is a non-invasive therapy leading, in most cases, to adequate clinical results, safety, and tolerability, sclerotherapy with MEO can be considered an effective treatment for BOVL.

Co-existence of cheilitis glandularis and actinic cheilitis-an update.

Cheilitis Glandularis (CG) is a chronic inflammatory disorder with no specific etiology that affects the minor salivary glands of the lips. The main characteristic of this condition consists of the exit of thick saliva or mucopurulent secretion through the dilated ducts present in the vermilion border of the lip, associated to varying degrees of macrocheilia. In this article we report the case of a male patient, leucoderma, 48 years old, that exhibited actinic cheilitis and glandular cheilitis. We emphasized the clinical management, diagnosis criteria and treatment, taking into consideration that GC is a rare condition and makes a differential diagnosis with other entities that may occur on lips. Although a diagnosis of CG is not difficult, its treatment is a challenge, considering the unknown etiology that hinders the development of more specific and effective treatments.

Caracterización de diagnóstico tardío de cáncer oral en una ciudad brasileña / Characterization of late diagnosis of oral cancer in a Brazilian city

Introduction: oral cancer in Brazil still presents high incidence and mortality rates and has different characteristics throughout the national territory. Although in most cases the diagnosis is late, there is a great possibility for cure when patients are treated early. Objective: to describe the sociodemographic profile of patients with oral squamous cell carcinoma and the possible etiological factors associated. Methods: this was a descriptive prospective cross-sectional study carried out in Napoleão Laureano Hospital, state of Paraíba, from January 2012 to May 2013. The study included patients with advanced-stage oral squamous cell carcinoma identified during clinical examination and confirmed by histopathology. The following variables were assessed: age, sex, comorbidity, smoking, alcohol use, tumor location, time of development, clinical staging, histopathological grading and proposed treatment. Results: a total of 15 cases of patients with stage III and IV oral squamous cell carcinoma were found. Of these, 80 percent were males with a mean age of 62.59 years and lesions affecting predominantly the mouth floor, followed by the tongue. The most common sign was the presence of tumor greater than 3.0-cm diameter, including ulcerated, leukoplastic and erythroplastic areas, in addition to pain and difficulty in feeding and phonation. Conclusion: the majority of patients identified, with advanced-stage squamous cell carcinoma showed moderate cellular differentiation between stages III and IV, and was composed by males with smoking and alcohol drinking habits in the seventh decade of life(AU)

Introducción: el cáncer oral en Brasil todavía presenta altos niveles de incidencia y mortalidad y tiene diferentes rasgos en todo el territorio nacional. En la mayoría de los casos el diagnóstico es tardío. Sin embargo, hay una gran posibilidad de cura cuando es tratado desde el principio. Objetivo: describir el perfil sociodemográfico de los pacientes afectados por carcinoma bucal de células escamosas, así como los posibles factores etiológicos asociados. Métodos: se realizó un estudio descriptivo prospectivo transversal en el hospital Dr. Napoleão Laureano, estado de Paraíba, desde enero de 2012 a mayo de 2013. El estudio incluyó a pacientes con carcinoma oral de células escamosas en estadio avanzado identificado durante el examen clínico y confirmado por histopatología. Se evaluaron las siguientes variables: edad, sexo, comorbilidad, el tabaquismo, el consumo de alcohol, la ubicación del tumor, el tiempo de desarrollo, la estadificación clínica, clasificación histopatológica y el tratamiento propuesto. Resultados: se encontró un total de 15 casos de pacientes con estadio III y IV del carcinoma oral de células escamosas COCE . De estos, 80 por ciento eran hombres con una edad media de 62,59 años. Las lesiones afectaban predominantemente al piso de la boca, seguido de la lengua. El signo clínico más común fue la presencia de tumor mayor que 3,0 cm de diámetro, incluyendo las zonas ulceradas, áreas con leucoplasia y eritroplasia, además de dolor y dificultad en la alimentación y la fonación. Conclusión: la mayoría de los pacientes identificados con carcinoma de células escamosas en estadio avanzado mostró moderada diferenciación celular entre los estadios III y IV. Estos eran hombres con hábitos de fumar y beber en la séptima década de la vida(AU)